• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

大鼠脊髓背根终末中的血管活性肠肽受外周神经轴浆运输的调节。

Vasoactive intestinal polypeptide in dorsal root terminals of the rat spinal cord is regulated by the axoplasmic transport in the peripheral nerve.

作者信息

Knyihár-Csillik E, Kreutzberg G W, Raivich G, Csillik B

机构信息

Department of Anatomy, Albert Szent-Györgyi Medical University, Szeged, Hungary.

出版信息

Neurosci Lett. 1991 Sep 30;131(1):83-7. doi: 10.1016/0304-3940(91)90342-q.

DOI:10.1016/0304-3940(91)90342-q
PMID:1724307
Abstract

Vasoactive intestinal polypeptide (VIP) immunoreactivity in the upper spinal dorsal horn is markedly increased after transection, crush or vinblastine treatment of the ipsilateral, segmentally related peripheral nerve. After regeneration of the peripheral nerve, VIP disappears from the upper dorsal horn. Transection-induced VIP increase is abolished by rhizotomy. It is concluded that the expression of VIP is restricted by factor(s) carried by retrograde axoplasmic transport to dorsal root ganglion cells.

摘要

在对同侧节段相关的周围神经进行横断、挤压或长春花碱处理后，脊髓背角上部的血管活性肠肽（VIP）免疫反应性显著增加。周围神经再生后，VIP从背角上部消失。横断诱导的VIP增加通过神经根切断术而消除。得出的结论是，VIP的表达受到通过逆行轴浆运输携带至背根神经节细胞的因子的限制。

相似文献

1
Vasoactive intestinal polypeptide in dorsal root terminals of the rat spinal cord is regulated by the axoplasmic transport in the peripheral nerve.大鼠脊髓背根终末中的血管活性肠肽受外周神经轴浆运输的调节。
Neurosci Lett. 1991 Sep 30;131(1):83-7. doi: 10.1016/0304-3940(91)90342-q.
2
Vasoactive intestinal polypeptide (VIP) increases in the spinal cord after peripheral axotomy of the sciatic nerve originate from primary afferent neurons.坐骨神经外周轴突切断后，脊髓中源自初级传入神经元的血管活性肠肽（VIP）增加。
Brain Res. 1986 Apr 30;372(1):37-44. doi: 10.1016/0006-8993(86)91456-3.
3
A case for transmitter plasticity at the molecular level: axotomy-induced VIP increase in the upper spinal dorsal horn is related to blockade of retrograde axoplasmic transport of nerve growth factor in the peripheral nerve.分子水平上递质可塑性的一个实例：轴突切断术引起的脊髓背角浅层血管活性肠肽增加与外周神经中神经生长因子逆行轴浆运输受阻有关。
Acta Histochem. 1991;91(1):77-83. doi: 10.1016/S0065-1281(11)80299-0.
4
Fine structural correlates of VIP-like immunoreactivity in the upper spinal dorsal horn after peripheral axotomy: possibilities of a neuro-glial translocation of a neuropeptide.外周轴突切断后脊髓背角上部血管活性肠肽样免疫反应性的超微结构相关性：神经肽神经胶质易位的可能性
Acta Histochem. 1993 Feb;94(1):1-12. doi: 10.1016/s0065-1281(11)80332-6.
5
Neuropeptide expression in rat dorsal root ganglion cells and spinal cord after peripheral nerve injury with special reference to galanin.外周神经损伤后大鼠背根神经节细胞和脊髓中的神经肽表达，特别提及甘丙肽
Neuroscience. 1989;33(3):587-604. doi: 10.1016/0306-4522(89)90411-9.
6
Alterations in glial fibrillary acidic protein immunoreactivity in the upper dorsal horn of the rat spinal cord in the course of transganglionic degenerative atrophy and regenerative proliferation.在跨神经节变性萎缩和再生性增殖过程中大鼠脊髓上背角胶质纤维酸性蛋白免疫反应性的变化
Neurosci Lett. 1990 Sep 4;117(1-2):8-13. doi: 10.1016/0304-3940(90)90111-l.
7
Axonal blockade induces the expression of vasoactive intestinal polypeptide and galanin in rat dorsal root ganglion neurons.
Brain Res. 1992 Apr 10;577(1):19-28. doi: 10.1016/0006-8993(92)90532-e.
8
Primary afferent origin of substance P-containing axons in the superficial dorsal horn of the rat spinal cord: depletion, regeneration and replenishment of presumed nociceptive central terminals.大鼠脊髓浅表背角含P物质轴突的初级传入起源：假定伤害性中枢终末的耗竭、再生与补充
J Comp Neurol. 1990 Jul 22;297(4):594-612. doi: 10.1002/cne.902970411.
9
Growth of myelinated lumbosacral ventral root fibers in kittens after early postnatal dorsal rhizotomy, dorsal rhizotomy and spinal cord hemisection, or sciatic neurectomy.出生后早期进行背根切断术、背根切断术与脊髓半横断术或坐骨神经切除术的小猫中，有髓腰荐腹侧根纤维的生长情况。
Exp Neurol. 1976 Oct;53(1):189-213. doi: 10.1016/0014-4886(76)90292-2.
10
Co-localized but target-unrelated expression of vasoactive intestinal polypeptide and galanin in rat dorsal root ganglion neurons after peripheral nerve crush injury.
Brain Res. 1992 Jun 5;582(1):47-57. doi: 10.1016/0006-8993(92)90315-z.

引用本文的文献

1
NT-3 modulates NPY expression in primary sensory neurons following peripheral nerve injury.在周围神经损伤后，神经营养因子-3调节初级感觉神经元中神经肽Y的表达。
J Anat. 1998 Aug;193 ( Pt 2)(Pt 2):273-81. doi: 10.1046/j.1469-7580.1998.19320273.x.
2
Expression of neuropeptides and neuropeptide mRNAs in spinal cord after axotomy in the rat, with special reference to motoneurons and galanin.大鼠轴突切断后脊髓中神经肽及神经肽mRNA的表达，特别涉及运动神经元和甘丙肽
Exp Brain Res. 1993;93(3):450-61. doi: 10.1007/BF00229360.