Baad-Hansen L, Jadidi F, Castrillon E, Thomsen P B, Svensson P
Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Aarhus C, Denmark.
J Oral Rehabil. 2007 Feb;34(2):105-11. doi: 10.1111/j.1365-2842.2006.01717.x.
The nociceptive trigeminal inhibitory (NTI) splint has been claimed to decrease the electromyographic (EMG) activity of jaw-closing muscles and relieve symptoms of various types of temporomandibular disorders (TMD) and bruxism. The present study was designed to address the question about EMG-changes during sleep. Ten patients (age: 23-39 years) with a self-report of tooth-grinding during sleep were recruited. Patients were examined at baseline and after each treatment period with the use of the Research Diagnostic Criteria for TMD. A portable EMG-device was used to record EMG-activity from the masseter muscle during sleep. The patients received two 2-week splint treatments in a randomized cross-over fashion; an NTI splint and a standard flat occlusal splint (OS). EMG data were analysed according to published criteria. Using a 10% of maximum clenching EMG-activity cut-off threshold to determine the number of EMG-events h(-1) of sleep, the NTI splint was associated with a significant reduction (9.2 +/- 3.2 events h(-1)) compared with baseline EMG (19.3 +/- 4.0; anova: P = 0.004, Tukey post hoc: P = 0.006), whereas there were no differences between the OS (16.2 +/- 4.7) and baseline EMG (19.2 +/- 4.1; P = 0.716). There were no effects of either NTI or OS on clinical outcome measures (anovas: P > 0.194). This short-term study indicated a strong inhibitory effect on EMG-activity in jaw closing muscles during sleep of the NTI, but not the OS. However, the EMG-activity was not directly related to clinical outcome. Further studies will be needed to determine long-term effects and possible side effects of the NTI splint.
伤害性三叉神经抑制（NTI）牙合板据称可降低闭口肌的肌电图（EMG）活动，并缓解各种类型颞下颌关节紊乱病（TMD）和磨牙症的症状。本研究旨在探讨睡眠期间EMG的变化情况。招募了10名自述有睡眠磨牙的患者（年龄：23 - 39岁）。在基线期以及每个治疗阶段结束后，依据TMD研究诊断标准对患者进行检查。使用便携式EMG设备记录睡眠期间咬肌的EMG活动。患者以随机交叉方式接受两种为期2周的牙合板治疗，即NTI牙合板和标准平牙合垫（OS）。根据已发表的标准对EMG数据进行分析。使用最大紧咬EMG活动的10%作为截止阈值来确定睡眠中每小时EMG事件的数量，与基线EMG（19.3±4.0）相比，NTI牙合板可使EMG事件显著减少（9.2±3.2次/小时）（方差分析：P = 0.004，Tukey事后检验：P = 0.006），而OS（16.2±4.7）与基线EMG（19.2±4.1）之间无差异（P = 未找到该值，请确认原文）。NTI或OS对临床结局指标均无影响（方差分析：P > 0.194）。这项短期研究表明，NTI对睡眠期间闭口肌的EMG活动有强烈抑制作用，而OS则无此作用。然而，EMG活动与临床结局并无直接关联。需要进一步研究以确定NTI牙合板的长期效果和可能的副作用。
