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加拿大心血管学会2007年心力衰竭最新共识会议建议:预防、并发疾病或急性失代偿期间的管理以及生物标志物的应用。

Canadian Cardiovascular Society Consensus Conference recommendations on heart failure update 2007: Prevention, management during intercurrent illness or acute decompensation, and use of biomarkers.

作者信息

Arnold J Malcom O, Howlett Jonathan G, Dorian Paul, Ducharme Anique, Giannetti Nadia, Haddad Haissam, Heckman George A, Ignaszewski Andrew, Isaac Debra, Jong Philip, Liu Peter, Mann Elizabeth, McKelvie Robert S, Moe Gordon W, Parker John D, Svendsen Anna M, Tsuyuki Ross T, O'Halloran Kelly, Ross Heather J, Rao Vivek, Sequeira Errol J, White Michel

机构信息

University of Western Ontario, London, Canada.

出版信息

Can J Cardiol. 2007 Jan;23(1):21-45. doi: 10.1016/s0828-282x(07)70211-8.

Abstract

Heart failure is common, yet it is difficult to treat. It presents in many different guises and circumstances in which therapy needs to be individualized. The Canadian Cardiovascular Society published a comprehensive set of recommendations in January 2006 on the diagnosis and management of heart failure, and the present update builds on those core recommendations. Based on feedback obtained through a national program of heart failure workshops during 2006, several topics were identified as priorities because of the challenges they pose to health care professionals. New evidence-based recommendations were developed using the structured approach for the review and assessment of evidence adopted and previously described by the Society. Specific recommendations and practical tips were written for the prevention of heart failure, the management of heart failure during intercurrent illness, the treatment of acute heart failure, and the current and future roles of biomarkers in heart failure care. Specific clinical questions that are addressed include: which patients should be identified as being at high risk of developing heart failure and which interventions should be used? What complications can occur in heart failure patients during an intercurrent illness, how should these patients be monitored and which medications may require a dose adjustment or discontinuation? What are the best therapeutic, both drug and nondrug, strategies for patients with acute heart failure? How can new biomarkers help in the treatment of heart failure, and when and how should BNP be measured in heart failure patients? The goals of the present update are to translate best evidence into practice, to apply clinical wisdom where evidence for specific strategies is weaker, and to aid physicians and other health care providers to optimally treat heart failure patients to result in a measurable impact on patient health and clinical outcomes in Canada.

摘要

心力衰竭很常见,但治疗困难。它以多种不同的形式和情况出现,治疗需要个体化。加拿大心血管学会于2006年1月发布了一套关于心力衰竭诊断和管理的全面建议,本次更新以这些核心建议为基础。根据2006年通过全国心力衰竭研讨会计划获得的反馈,由于某些主题给医疗保健专业人员带来了挑战,因此被确定为优先事项。新的循证建议是采用该学会采用并先前描述的证据审查和评估结构化方法制定的。针对心力衰竭的预防、并发疾病期间心力衰竭的管理、急性心力衰竭的治疗以及生物标志物在心力衰竭护理中的当前和未来作用,撰写了具体建议和实用提示。所解决的具体临床问题包括:哪些患者应被确定为有发生心力衰竭的高风险,应采用哪些干预措施?心力衰竭患者在并发疾病期间可能出现哪些并发症,应如何监测这些患者,哪些药物可能需要调整剂量或停药?对于急性心力衰竭患者,最佳的治疗策略(包括药物和非药物)是什么?新的生物标志物如何有助于心力衰竭的治疗,以及在心力衰竭患者中何时以及如何测量脑钠肽(BNP)?本次更新的目标是将最佳证据转化为实践,在特定策略的证据较弱时应用临床智慧,并帮助医生和其他医疗保健提供者优化治疗心力衰竭患者,从而对加拿大患者的健康和临床结果产生可衡量的影响。

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