Trepanier L A
New York State College of Veterinary Medicine, Department of Clinical Sciences, Ithaca 14853.
Probl Vet Med. 1990 Dec;2(4):668-82.
Antithyroid drugs are widely used in human medicine for the medical management of Graves' disease. Because patients with Graves' disease may undergo spontaneous remission, antithyroid drugs are preferred for long-term therapy because they do not permanently affect thyroid function. Hyperthyroidism in cats is somewhat different, in that spontaneous remission has not been reported and therefore ablative treatment (surgery or radioiodine) is often preferred. However, antithyroid drugs are essential for preoperative stabilization of cats with hyperthyroidism and often are used for long-term management of certain cases. This chapter will review the various drugs available for the medical management of hyperthyroidism, their mechanisms of action, indications for use, and adverse side effects.
抗甲状腺药物在人类医学中被广泛用于格雷夫斯病的药物治疗。由于格雷夫斯病患者可能会自发缓解，抗甲状腺药物因不会永久性影响甲状腺功能而更适合长期治疗。猫的甲状腺功能亢进情况有所不同，因为尚未有自发缓解的报道，因此通常更倾向于采用消融治疗（手术或放射性碘治疗）。然而，抗甲状腺药物对于甲状腺功能亢进猫的术前稳定至关重要，并且常用于某些病例的长期管理。本章将综述可用于甲状腺功能亢进药物治疗的各种药物、它们的作用机制、使用指征以及不良反应。
