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[HIV-1 诱导的淋巴结病的组织学分类。生发中心变化发病机制的当前研究结果]

[Histologic classification of HIV-1 induced lymphadenopathy. Current results on the pathogenesis of germinal center changes].

作者信息

Tenner-Racz K, Brachtel E, Racz P

机构信息

Abteilung für Hämatologie, Allgemeines Krankenhaus St. Georg, Hamburg.

出版信息

Verh Dtsch Ges Pathol. 1991;75:69-79.

PMID:1724855
Abstract

At the IV International Conference on AIDS in Stockholm, a Symposium on the pathology of HIV-related diseases was organized. During this Symposium the "European Study Group on HIV-Pathology" presented a histological classification of lymph node alterations seen in HIV-associated lymphadenopathy. The goal of the Study group was to offer a common terminology for histologic changes previously described with different terms by different authors. In the present review the most important histological criteria used in the proposed classification are summarized. Since the classification is based on the conspicuous changes of the follicles, a brief review of the possible pathogenic mechanisms leading to disintegration of the germinal centers will also be given.

摘要

在斯德哥尔摩召开的第四届国际艾滋病会议上,组织了一场关于HIV相关疾病病理学的研讨会。在这次研讨会上,“欧洲HIV病理学研究小组”提出了HIV相关淋巴结病中所见淋巴结改变的组织学分类。该研究小组的目标是为先前不同作者用不同术语描述的组织学变化提供一个通用术语。在本综述中,总结了所提议分类中使用的最重要的组织学标准。由于该分类基于滤泡的显著变化,因此还将简要回顾导致生发中心解体的可能致病机制。

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