Walewska-Zielecka B, Nowosławski A
Department of Immunopathology, National Institute of Hygiene, Warszawa.
Pol J Pathol. 1995;46(4):211-7.
Lymph nodes from 65 HIV-infected persons were studied by morphological and immunomorphological methods. Early stages of HIV lymphadenopathy (follicular hyperplasia without fragmentation or follicular hyperplasia with severe fragmentation) were revealed in 92% of patients with PGL and the most advanced stadium of HIV-related lymphadenopathy (diffuse pattern) in 92% of AIDS patients. Striking B-cell activation and polyclonal proliferation, found in 19 lymph nodes (35% of advanced lymphadenopathy cases--follicular atrophy or diffuse pattern) justified separation of these cases as a particular subgroup of HIV lymphadenopathy.
采用形态学和免疫形态学方法对65例HIV感染者的淋巴结进行了研究。在92%的PGL患者中发现了HIV淋巴结病的早期阶段（无碎片的滤泡增生或伴有严重碎片的滤泡增生），在92%的AIDS患者中发现了HIV相关淋巴结病的最晚期阶段（弥漫型）。在19个淋巴结中发现的显著B细胞活化和多克隆增殖（占晚期淋巴结病病例的35%——滤泡萎缩或弥漫型）证明将这些病例作为HIV淋巴结病的一个特殊亚组进行区分是合理的。
