黑腹果蝇 Y 染色体的遗传和细胞学组织。
The Genetic and Cytological Organization of the Y Chromosome of DROSOPHILA MELANOGASTER.
机构信息
Department of Biology, University of California, San Diego, La Jolla, California 92093.
出版信息
Genetics. 1981 Jul;98(3):529-48. doi: 10.1093/genetics/98.3.529.
Abstract
Cytological and genetic analyses of 121 translocations between the Y chromosome and the centric heterochromatin of the X chromosome have been used to define and localize six regions on the Y chromosome of Drosophila melanogaster necessary for male fertility. These regions are associated with nonfluorescent blocks of the Y chromosome, as revealed using Hoechst 33258 or quinacrine staining. Each region appears to contain but one functional unit, as defined by failure of complementation among translocations with breakpoints within the same block. The distribution of translocation breakpoints examined appears to be nonrandom, in that breaks occur preferentially in the nonfluorescent blocks and not in the large fluorescent blocks.
摘要
细胞学和遗传学分析了 121 条 Y 染色体与 X 染色体着丝粒异染色质之间的易位，这些分析用于鉴定和定位黑腹果蝇 Y 染色体上的 6 个必需区域，这些区域与 Y 染色体的非荧光块有关，这是通过使用 Hoechst 33258 或吖啶橙染色发现的。每个区域似乎只包含一个功能单元，这是通过同一块内断点的易位之间的互补失败来定义的。所检查的易位断点的分布似乎是随机的，因为断裂优先发生在非荧光块中，而不是在大的荧光块中。
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