Chakravarty J, Mehta H, Parekh A, Attili S V S, Agrawal N R, Singh S P, Sundar S
Department of Medicine, Banaras Hindu University, Varanasi.
J Assoc Physicians India. 2006 Nov;54:854-7.
In this study, 438 HIV positive patients attending the HIV clinic of Sir Sundar Lal Hospital, IMS, BHU were enrolled. Of these 354 were males (mean CD4 count 179 +/- 9.3 cells/microl) and 84 were females (mean CD4 count 323 +/- 28.26 cells/microl). The mean age of the study subjects at the time of diagnosis was 32.6 years. Heterosexual contact was the commonest mode of transmission in 352 (80.4%) patients followed by blood transfusion in 2.5%. History suggestive of a risk factor for HIV transmission could not be elicited in 62 (14.1%) patients. Among male patients, 71.5% were migrant workers. Fever (70.6%), weight loss (53.3%), chronic diarrhea (43.9%) and cough (40.3%) were the common presenting symptoms. Out of the 438 patients, 66.4% had opportunistic infections at the time of reporting to the hospital. The most common opportunistic infection was tuberculosis (38.8%) followed by oropharyngeal candidiasis (20.3%) and diarrhea (12.7%). CD4 counts of the patients were significantly inversely correlated with the number of symptoms and the number of opportunistic infections (correlation coefficient were -.289 and -.236 respectively).
在本研究中，纳入了印度贝拿勒斯印度教大学医学院下属苏达·拉尔爵士医院艾滋病诊所的438名HIV阳性患者。其中354名男性（平均CD4细胞计数为179±9.3个/微升），84名女性（平均CD4细胞计数为323±28.26个/微升）。研究对象确诊时的平均年龄为32.6岁。异性接触是352名（80.4%）患者最常见的传播方式，其次是输血，占2.5%。62名（14.1%）患者无法引出提示HIV传播危险因素的病史。男性患者中，71.5%是农民工。发热（70.6%）、体重减轻（53.3%）、慢性腹泻（43.9%）和咳嗽（40.3%）是常见的首发症状。在438名患者中，66.4%在入院时患有机会性感染。最常见的机会性感染是结核病（38.8%），其次是口腔念珠菌病（20.3%）和腹泻（12.7%）。患者的CD4细胞计数与症状数量和机会性感染数量显著负相关（相关系数分别为-0.289和-0.236）。
