Sandler J A, Gallin J I, Vaughan M
J Cell Biol. 1975 Nov;67(2PT.1):480-4. doi: 10.1083/jcb.67.2.480.
Serotonin, ascorbic acid, and carbamylcholine enhanced the chemotactic responsiveness of human monocytes to endotoxin-treated serum. These agents caused significant accumulation of cyclic GMP in monocytes. PMN leukocyte chemotaxis was also enhanced by these agents although significant increases in cyclic GMP were not demonstrated.
血清素、抗坏血酸和氨甲酰胆碱增强了人类单核细胞对内毒素处理血清的趋化反应性。这些物质导致单核细胞中环状鸟苷酸大量积累。这些物质也增强了中性粒细胞的趋化性,尽管未显示环状鸟苷酸有显著增加。