血清素（5-羟色胺）及其衍生物对人单核细胞中鸟苷3',5'-单磷酸的影响。
The effect of serotonin (5-hydroxytryptamine) and derivatives on guanosine 3',5'-monophosphate in human monocytes.
作者信息
Sandler J A, Clyman R I, Manganiello V C, Vaughan M
出版信息
J Clin Invest. 1975 Feb;55(2):431-5. doi: 10.1172/JCI107948.
Abstract
The effects of several putative mediators of inflammatory responses on the cyclic nucleotide content of mononuclear leukocytes from human peripheral blood were investigated. Incubation of mononuclear cells with 100 muM serotonin (a maximally effective concentration) for 5 min caused a five- to eightfold increase in their content of guanosine 3',5'-monophosphate (cAMP)...
摘要
研究了几种假定的炎症反应介质对人外周血单个核白细胞环核苷酸含量的影响。将单个核细胞与100μM血清素（最大有效浓度）孵育5分钟，导致其3',5'-环磷酸鸟苷（cAMP）含量增加5至8倍……
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本文引用的文献
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The transformation of column-purified lymphocytes with nonspecific and specific antigenic stimuli.用非特异性和特异性抗原刺激对柱纯化淋巴细胞进行转化。
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The percentage of monocytes among "mononuclear" cell fractions obtained from normal human blood.从正常人血液中获得的“单核”细胞组分中单核细胞的百分比。
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Hormonal control of lysosomal enzyme release from human neutrophils. Effects of autonomic agents on enzyme release, phagocytosis, and cylic nucleotide levels.人中性粒细胞溶酶体酶释放的激素控制。自主神经药物对酶释放、吞噬作用和环核苷酸水平的影响。
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