Woodall John, McCarthy Molly, Johnston Trisha, Tippett Vivienne, Bonham Richard
Australian Centre for Prehospital Research, GPO Box 1425, Brisbane, Queensland 4001, Australia.
Emerg Med J. 2007 Feb;24(2):134-8. doi: 10.1136/emj.2005.033365.
Prehospital research has found little evidence in support of advanced cardiac life support (ACLS) for out-of-hospital cardiac arrest. However, these studies generally examine city-based emergency medical services (EMS) systems. The training and experience of ACLS-skilled paramedics differs internationally, and this may also contribute to negative findings. Additionally, the frequency of negative outcome in out-of-hospital cardiac arrest suggests that it is difficult to establish sufficient numbers to detect an effect.
To examine the effect of ACLS on cardiac arrest in Queensland, Australia. Queensland has a population of 3.8 million and an area of over 1.7 million km2, and is served by a statewide EMS system, which deploys resources using a two-tier model. Advanced treatments such as intubation and cardioactive drug administration are provided by extensively trained intensive care paramedics.
An observational, retrospective design was used to examine all cases of cardiac arrest attended by the Queensland Ambulance Service from January 2000 to December 2002. Logistic regression was used to examine the effect of the presence of an intensive care paramedic on survival to hospital discharge, adjusting for age, sex, initial rhythm, the presence of a witness and bystander cardiopulmonary resuscitation.
The presence of an intensive care paramedic had a significant effect on survival (OR = 1.43, 95% CI = 1.02 to 1.99).
Highly trained ACLS-skilled paramedics provide added survival benefit in EMS systems not optimised for early defibrillation. The reasons for this benefit are multifactorial, but may be the result of greater skill level and more informed use of the full range of prehospital interventions.
院前研究几乎没有发现证据支持对院外心脏骤停患者实施高级心脏生命支持(ACLS)。然而,这些研究通常考察的是城市地区的紧急医疗服务(EMS)系统。具备ACLS技能的护理人员的培训和经验在国际上存在差异,这也可能导致出现负面研究结果。此外,院外心脏骤停不良结局的发生率表明,很难纳入足够数量的病例以检测出某种效果。
考察ACLS对澳大利亚昆士兰州心脏骤停患者的影响。昆士兰州人口为380万,面积超过170万平方公里,由一个覆盖全州的EMS系统提供服务,该系统采用两级模式调配资源。诸如插管和使用心血管活性药物等高级治疗由经过广泛培训的重症护理人员提供。
采用观察性回顾性设计,考察昆士兰救护服务机构在2000年1月至2002年12月期间接诊的所有心脏骤停病例。使用逻辑回归分析考察重症护理人员的在场情况对存活至出院的影响,并对年龄、性别、初始心律、是否有目击者以及旁观者心肺复苏情况进行校正。
重症护理人员的在场情况对存活有显著影响(比值比=1.43,95%置信区间=1.02至1.99)。
在未优化早期除颤的EMS系统中,训练有素、具备ACLS技能的护理人员能带来额外的生存获益。这种获益的原因是多方面的,但可能是更高技能水平以及更明智地使用全套院前干预措施的结果。