Srikrishnan Thamarapu, Mackenzie James T, Sulkowski Eugene
Department of Cancer Biology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.
J Chromatogr Sci. 2006 Nov-Dec;44(10):634-8, 3A. doi: 10.1093/chromsci/48.2.634.
Lactoferrin and serum transferrin, the iron-binding proteins, are widely distributed in biological fluids. Transferrins have many biological functions: anti-bacterial, anti-inflammatory, and immunoregulatory. A facile monitoring of the concentration of transferrins in biological fluids may have medical relevance. Thiophilic-interaction chromatography of transferrins may provide an efficient means for their quantitation in serum.
乳铁蛋白和血清转铁蛋白这两种铁结合蛋白广泛分布于生物体液中。转铁蛋白具有多种生物学功能：抗菌、抗炎和免疫调节。对生物体液中转铁蛋白浓度进行简便监测可能具有医学意义。转铁蛋白的嗜硫相互作用色谱法可能为其在血清中的定量分析提供一种有效方法。
