Srikrishnan Thamarapu, Mackenzie James T, Sulkowski Eugene
Department of Cancer Biology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.
J Chromatogr Sci. 2006 Nov-Dec;44(10):634-8, 3A. doi: 10.1093/chromsci/48.2.634.
Lactoferrin and serum transferrin, the iron-binding proteins, are widely distributed in biological fluids. Transferrins have many biological functions: anti-bacterial, anti-inflammatory, and immunoregulatory. A facile monitoring of the concentration of transferrins in biological fluids may have medical relevance. Thiophilic-interaction chromatography of transferrins may provide an efficient means for their quantitation in serum.