Yamamoto Yasuo, Kurazono Mizuyo
Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd, 760 Morooka-cho, Kohoku-ku, Yokohama 222-8567, Japan.
Bioorg Med Chem Lett. 2007 Mar 15;17(6):1626-8. doi: 10.1016/j.bmcl.2006.12.081. Epub 2007 Jan 4.
A new class of indole-containing compounds were prepared by the use of three component reaction and their in vitro antibacterial activities (MIC) were evaluated against Staphylococcus aureus and Enterococcus faecium including MRSA and VRE.
通过三组分反应制备了一类新型含吲哚化合物,并评估了它们对金黄色葡萄球菌和粪肠球菌(包括耐甲氧西林金黄色葡萄球菌和耐万古霉素肠球菌)的体外抗菌活性(最低抑菌浓度)。