Gawande Atul A, Kwaan Mary R, Regenbogen Scott E, Lipsitz Stuart A, Zinner Michael J
Department of Health Policy and Management, Harvard School of Public Health, Boston, MA, USA.
J Am Coll Surg. 2007 Feb;204(2):201-8. doi: 10.1016/j.jamcollsurg.2006.11.011. Epub 2006 Dec 27.
Surgical teams have not had a routine, reliable measure of patient condition at the end of an operation. We aimed to develop an Apgar score for the field of surgery, an outcomes score that teams could calculate at the end of any general or vascular surgical procedure to accurately grade a patient's condition and chances of major complications or death.
We derived our surgical score in a retrospective analysis of data from medical records and the National Surgical Quality Improvement Program for 303 randomly selected patients undergoing colectomy at Brigham and Women's Hospital, Boston. The primary outcomes measure was incidence of major complication or death within 30 days of operation. We validated the score in two prospective, randomly selected cohorts: 102 colectomy patients and 767 patients undergoing general or vascular operations at the same institution.
A 10-point score based on a patient's estimated amount of blood loss, lowest heart rate, and lowest mean arterial pressure during general or vascular operations was significantly associated with major complications or death within 30 days (p < 0.0001; c-index = 0.72). Of 767 general and vascular surgery patients, 29 (3.8%) had a surgical score <or= 4. Major complications or death occurred in 17 of these 29 patients (58.6%) within 30 days. By comparison, among 220 patients with scores of 9 or 10, only 8 (3.6%) experienced major complications or died (relative risk 16.1; 95% CI, 7.6-34.0; p < 0.0001).
A simple score based on blood loss, heart rate, and blood pressure can be useful in rating the condition of patients after general or vascular operations.
手术团队在手术结束时一直没有对患者状况进行常规、可靠测量的方法。我们旨在开发一种适用于外科领域的阿普加评分,这是一种手术结果评分,手术团队可在任何普通外科或血管外科手术结束时进行计算,以准确评估患者的状况以及发生重大并发症或死亡的可能性。
我们通过对波士顿布莱根妇女医院303例随机选取的接受结肠切除术患者的病历数据和国家外科质量改进计划进行回顾性分析得出了我们的手术评分。主要观察指标为术后30天内发生重大并发症或死亡的发生率。我们在两个前瞻性随机选取的队列中对该评分进行了验证:102例结肠切除术患者以及同一机构的767例接受普通外科或血管外科手术的患者。
基于患者在普通外科或血管外科手术期间估计失血量、最低心率和最低平均动脉压得出的10分评分与术后30天内发生重大并发症或死亡显著相关(p<0.0001;c指数=0.72)。在767例普通外科和血管外科手术患者中,29例(3.8%)的手术评分为4分或更低。这29例患者中有17例(58.6%)在30天内发生了重大并发症或死亡。相比之下,在220例评分为9分或10分的患者中,只有8例(3.6%)发生了重大并发症或死亡(相对风险16.1;95%可信区间,7.6 - 34.0;p<0.0001)。
基于失血量、心率和血压的简单评分可用于评估普通外科或血管外科手术后患者的状况。