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手术阿普加评分结果:根治性膀胱切除术的围手术期风险评估

Surgical apgar outcome score: perioperative risk assessment for radical cystectomy.

作者信息

Prasad Sandip M, Ferreria Marcos, Berry Alexander M, Lipsitz Stuart R, Richie Jerome P, Gawande Atul A, Hu Jim C

机构信息

Division of Urologic Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.

出版信息

J Urol. 2009 Mar;181(3):1046-52; discussion 1052-3. doi: 10.1016/j.juro.2008.10.165. Epub 2009 Jan 15.

Abstract

PURPOSE

Currently objective perioperative risk assessment metrics are lacking for radical cystectomy. Using a simple 10-point scale similar to neonatal Apgar assessment we evaluated whether a surgical outcome score calculated immediately after radical cystectomy would predict major complications and mortality.

MATERIALS AND METHODS

We identified 155 consecutive radical cystectomies performed between 2005 and 2007 at our institution. Data were collected on 45 preoperative and intraoperative variables. We used a framework established by the National Surgical Quality Improvement Program to evaluate major complications within 30 days of surgery. We used a 10-point scoring system that had been previously validated in general and vascular surgery populations, comprising estimated blood loss, lowest heart rate and lowest mean arterial pressure.

RESULTS

A total of 40 (26%) patients undergoing radical cystectomy experienced a major complication within 30 days of the operation. There was a progressive decrease in complications with increasing surgical Apgar score, in that patients with a low vs a high Apgar score were more likely to experience complications (OR 6.9, 95% CI 1.9-24.2). Coronary artery disease, American Society of Anesthesiologists class, intraoperative blood transfusion, volume of intravenous fluid administered and female gender were also associated with major complications (p <0.05).

CONCLUSIONS

In patients undergoing radical cystectomy the surgical Apgar score predicts major postoperative complications and death. This simple and objective postoperative metric may be used to dictate the intensity of care. Prospective studies are needed to determine whether treatment decisions based on this scoring system improve radical cystectomy outcomes.

摘要

目的

目前根治性膀胱切除术缺乏客观的围手术期风险评估指标。我们采用一种类似于新生儿阿氏评分的简单10分制量表,评估根治性膀胱切除术后立即计算出的手术结果评分是否能预测主要并发症和死亡率。

材料与方法

我们确定了2005年至2007年在我们机构连续进行的155例根治性膀胱切除术。收集了45项术前和术中变量的数据。我们使用国家外科质量改进计划建立的框架来评估术后30天内的主要并发症。我们使用了一个先前在普通外科和血管外科人群中得到验证的10分评分系统,该系统包括估计失血量、最低心率和最低平均动脉压。

结果

共有40例(26%)接受根治性膀胱切除术的患者在术后30天内发生了主要并发症。随着手术阿氏评分的增加,并发症逐渐减少,即阿氏评分低的患者比评分高的患者更易发生并发症(比值比6.9,95%可信区间1.9-24.2)。冠状动脉疾病、美国麻醉医师协会分级、术中输血、静脉输液量和女性性别也与主要并发症相关(p<0.05)。

结论

在接受根治性膀胱切除术的患者中,手术阿氏评分可预测术后主要并发症和死亡。这种简单而客观的术后指标可用于指导护理强度。需要进行前瞻性研究来确定基于该评分系统的治疗决策是否能改善根治性膀胱切除术的结果。

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