Bertin R, De Marco F, Laury M C, Portet R
Laboratoire d'Adaptation Energétique à l'Environnement, Ecole Pratique des Hautes Etudes, Paris, France.
Arch Int Physiol Biochim Biophys. 1991 Dec;99(6):479-82.
In order to determine the possible role of adrenal catecholamines in the enhancement of aldosterone production in cold acclimated rats, dopamine (DA), noradrenaline (NA) and adrenaline (A) contents of adrenals were investigated in cold acclimated (or not), hypophysectomized (or not) rats. The DA content, DA being an inhibitor of aldosterone synthesis, increased in hypophysectomized rats and remained unchanged in sham-operated ones following cold exposure. The NA and A contents, these being, in vitro, stimulators of aldosterone production did not increase, in either group of cold acclimated rats. It is concluded that adrenal catecholamines do not seem to be implicated in the enhancement of aldosterone production.
为了确定肾上腺儿茶酚胺在冷适应大鼠醛固酮分泌增加中可能发挥的作用，对冷适应（或未冷适应）、垂体切除（或未垂体切除）的大鼠肾上腺中的多巴胺（DA）、去甲肾上腺素（NA）和肾上腺素（A）含量进行了研究。DA是醛固酮合成的抑制剂，其含量在垂体切除的大鼠中增加，而在假手术大鼠冷暴露后保持不变。NA和A的含量，在体外是醛固酮分泌的刺激剂，在两组冷适应大鼠中均未增加。由此得出结论，肾上腺儿茶酚胺似乎与醛固酮分泌的增加无关。
