Schäfers Hans-Joachim, Aicher Diana, Langer Frank, Lausberg Henning F
Department of Thoracic and Cardiovascular Surgery, University Hospitals of Saarland, Homburg/Saar, Germany.
Ann Thorac Surg. 2007 Feb;83(2):S740-5; discussion S785-90. doi: 10.1016/j.athoracsur.2006.11.017.
Bicuspid anatomy of the aortic valve is a common reason for aortic regurgitation and is associated with aortic dilatation in more than 50% of patients. We have observed different patterns of aortic dilatation and used different approaches preserving the valve.
Between October 1995 and February 2006, a regurgitant bicuspid valve was repaired in 173 patients. The aorta was normal in 57 patients who underwent isolated repair. Aortic dilatation mainly above commissural level (n = 38) was treated by separate valve repair plus supracommissural aortic replacement. In 78 patients, aortic dilatation involved the root and was treated by root remodeling.
Hospital mortality and perioperative morbidity were low in all three groups. Myocardial ischemia was significantly shorter in repair plus aortic replacement than remodeling (p < 0.001). Freedom from aortic regurgitation II or greater at 5 years varied between 91% and 96%. Freedom from reoperation at 5 years was 97% after remodeling, but only 53% after repair plus aortic replacement (p = 0.33). Symmetric prolapse was the most frequent cause for reoperation.
The long-term stability of bicuspid aortic valve repair is excellent in the absence of aortic pathology. In the presence of aortic dilatation, root remodeling leads to equally stable valve durability. In patients with less pronounced root dilatation, separate valve repair plus aortic replacement may be a less complex alternative. Symmetric prolapse should be avoided if the ascending aorta is replaced.
主动脉瓣二叶式解剖结构是主动脉瓣反流的常见原因,超过50%的患者伴有主动脉扩张。我们观察到不同类型的主动脉扩张,并采用了不同的瓣膜保留方法。
1995年10月至2006年2月期间,173例患者接受了反流性二叶式瓣膜修复术。57例单纯接受修复术的患者主动脉正常。主要在瓣叶交界水平以上的主动脉扩张(n = 38)通过单独瓣膜修复加瓣叶交界上主动脉置换术治疗。78例主动脉扩张累及根部的患者接受了根部重塑术。
三组患者的住院死亡率和围手术期发病率均较低。修复加主动脉置换术患者的心肌缺血时间明显短于根部重塑术患者(p < 0.001)。5年时无中度或以上主动脉瓣反流的患者比例在91%至96%之间。根部重塑术后5年再次手术率为97%,但修复加主动脉置换术后仅为53%(p = 0.33)。对称性脱垂是再次手术的最常见原因。
在无主动脉病变的情况下,二叶式主动脉瓣修复术的长期稳定性极佳。存在主动脉扩张时,根部重塑术可使瓣膜耐久性同样稳定。对于根部扩张不明显的患者,单独瓣膜修复加主动脉置换术可能是一种复杂性较低的替代方案。如果升主动脉进行了置换,应避免对称性脱垂。