隐睾婴儿的垂体促黄体生成素、促卵泡生成素及睾酮分泌

Pituitary LH and FSH and testosterone secretion in infants with undescended testes.

作者信息

Job J C, Gendrel D, Safar A, Roger M, Chaussain J L

出版信息

Acta Endocrinol (Copenh). 1977 Jul;85(3):644-9. doi: 10.1530/acta.0.0850644.

DOI:10.1530/acta.0.0850644

Abstract

Twelve male infants with undescended testes (5 bilaterally, 7 unilaterally) were studied between the ages of 1 week and 11 months. As in older pre-pubertal cryptorchid boys, a significant decrease of the LH response to LH-RH test was found, while basal plasma levels of gonadotrophins and FSH response to LH-RH were normal. Plasma testosterone levels were in the normal range, and Leydig cells responded to stimulation by HCG, the degree of this response being significantly and positively correlated to the LH peak elicited by LH-RH. It may be concluded that some early defect of the pituitary-Leydig cell axis is associated with undescended testis.

摘要

对12例年龄在1周龄至11个月之间的隐睾男婴（5例双侧隐睾，7例单侧隐睾）进行了研究。与青春期前较大的隐睾男孩一样，发现促黄体生成素（LH）对促性腺激素释放激素（LH-RH）试验的反应显著降低，而促性腺激素的基础血浆水平以及促卵泡生成素（FSH）对LH-RH的反应正常。血浆睾酮水平在正常范围内，睾丸间质细胞对人绒毛膜促性腺激素（HCG）刺激有反应，这种反应程度与LH-RH引起的LH峰值呈显著正相关。可以得出结论，垂体-睾丸间质细胞轴的某些早期缺陷与隐睾有关。