Friedlander Arthur H, Cohen Stanley N
Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jun;103(6):830-5. doi: 10.1016/j.tripleo.2006.07.016. Epub 2007 Jan 29.
This study sought to determine if calcified carotid artery atheromas (CCAA) imaged on panoramic radiographs portend an adverse vascular event.
Medical records of 46 males (mean age 66) with a CCAA (Group 1) were reviewed for preimaging vascular risks and for cerebrovascular events subsequent to the radiograph. Matched controls (age, gender, ethnicity, and vascular risks) treated at the same hospital but never radiographed were identified (Group 2) and matched to their cohort. The medical records of Group 2 individuals were re-reviewed for development of vascular events occurring after the date of their cohort's radiograph.
Twenty adverse vascular events (myocardial infarct, stroke, revascularization procedure, transient ischemic attack, angina requiring hospitalization) occurred in twelve Group 1 patients and 6 events occurred in five Group 2 patients (P = 0.006).
The incidental finding of a CCAA portends significant risk of a future, adverse vascular event.
本研究旨在确定全景X线片上成像的钙化颈动脉粥样斑块(CCAA)是否预示着不良血管事件。
回顾了46名男性(平均年龄66岁)患有CCAA(第1组)的病历,以了解成像前的血管风险以及X线片后的脑血管事件。在同一家医院接受治疗但从未进行过X线检查的匹配对照(年龄、性别、种族和血管风险)被确定(第2组)并与其队列匹配。对第2组个体的病历进行重新审查,以了解其队列X线片日期后发生的血管事件。
12名第1组患者发生了20起不良血管事件(心肌梗死、中风、血运重建手术、短暂性脑缺血发作、需要住院治疗的心绞痛),5名第2组患者发生了6起事件(P = 0.006)。
CCAA的偶然发现预示着未来发生不良血管事件的重大风险。