Cohen Stanley N, Friedlander Arthur H, Jolly Desmond A, Date Lesley
Clinical Stroke Program, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Oct;94(4):510-4. doi: 10.1067/moe.2002.125580.
The objective of this study was to determine whether carotid calcifications are harbingers of future vascular events.
Between 1986 and 2000, 71 patients were found to have carotid artery calcifications on routine panoramic films. Medical records were reviewed for vascular risk factors existing before and vascular end points subsequent to the radiographs.
The mean age of our patients was 68 years. Sixty-one (86%) had preexisting vascular risk factors, 73% with multiple risk factors. Forty-one end points occurred in 29 patients. The average time to an end point was 2.7 years. The end points included myocardial infarction (8, 11%), stroke (5, 7%), death (11, 15%), revascularization procedures (8, 11%), transient ischemic attack (2, 3%), and angina (7, 10%). Twenty-three patients (34%) had major end points of myocardial infarction, stroke, or death.
Carotid calcifications identified on panoramic radiographs are powerful markers for subsequent vascular events. Patients found to have carotid calcification on panoramic radiographs should be referred for cerebrovascular and cardiovascular evaluation and aggressive management of vascular risk factors.
本研究的目的是确定颈动脉钙化是否为未来血管事件的先兆。
在1986年至2000年期间，71例患者在常规全景片上被发现有颈动脉钙化。回顾病历以了解在X光片之前存在的血管危险因素以及X光片之后的血管终点事件。
我们患者的平均年龄为68岁。61例（86%）有既往血管危险因素，73%有多种危险因素。29例患者发生了41次终点事件。至终点事件的平均时间为2.7年。终点事件包括心肌梗死（8例，11%）、中风（5例，7%）、死亡（11例，15%）、血管重建术（8例，11%）、短暂性脑缺血发作（2例，3%）和心绞痛（7例，10%）。23例患者（34%）发生了心肌梗死、中风或死亡等主要终点事件。
全景X光片上发现的颈动脉钙化是后续血管事件的有力标志物。在全景X光片上发现有颈动脉钙化的患者应转诊进行脑血管和心血管评估，并积极管理血管危险因素。
