Dept. of Maxillofacial Radiology, Faculty of Dentistry, Yeni Yuzyil University, Istanbul, Turkey.
Dept. of Cardiovascular Surgery, Private Western Anatolia Central Hospital, Izmir, Turkey.
Dentomaxillofac Radiol. 2020 May 1;49(4):20190440. doi: 10.1259/dmfr.20190440. Epub 2020 Feb 14.
To evaluate the diagnostic accuracy of digital panoramic radiograph (DPR) for detection of carotid artery calcification (CAC) confirmed by Doppler Ultrasonography (DUSG) and to clarify the relationship between between CAC identified by DPR and cardiovascular events through a 5 year follow-up period.
Of 3600 consecutive patients examined, 158 patients presented with CAC as detected by DPR. The final study group was composed of 96 patients who had CAC confirmed by DUSG or CT angiogram. The control group was composed of 62 patients who has normal DUSG. The end point of the study was the occurrence of any cardiovascular event.
72 (75%) of the 96 patients with CAC confirmed by DUSG (16 patients had significant stenosis) had bilateral and 24 (25%) had unilateral CAS as detected by DUSG. There was a low agreement between the examination results with a κ value of 0.488 ( < 0.005) for calcification. Study data revealed that smoking, chronic obstructive pulmonary disease (COPD), diabetes mellitus (DM) and diastolic hypertension were significantly more common in patients with CAC than the control group ( < 0.05). During the follow-up period, 13 subjects had myocardial infarction and 1 subject died; in the control group, 1 patient died after MI and 1 patient died of a non-cardiac event.
Patients with CAC detectable by DPR concomitant with COPD, DM, smoking or diastolic hypertension are more likely to suffer from vascular events. Therefore, patients with detectable carotid plaque in DPR require referral to a cardiovascular surgery clinic for further investigations.
评估数字全景 X 线摄影(DPR)检测经多普勒超声(DUSG)证实的颈动脉钙化(CAC)的诊断准确性,并通过 5 年随访期阐明 DPR 检测到的 CAC 与心血管事件之间的关系。
在 3600 例连续接受检查的患者中,有 158 例患者的 DPR 检测出 CAC。最终的研究组由 96 例经 DUSG 或 CT 血管造影证实 CAC 的患者组成。对照组由 62 例 DUSG 正常的患者组成。研究的终点是任何心血管事件的发生。
96 例经 DUSG 证实 CAC(16 例有明显狭窄)的患者中,72 例(75%)有双侧,24 例(25%)有单侧 CAS,DUSG 检测到的 CAC 有较低的一致性,κ 值为 0.488(<0.005)。研究数据显示,与对照组相比,CAC 患者中吸烟、慢性阻塞性肺疾病(COPD)、糖尿病(DM)和舒张期高血压更为常见(<0.05)。在随访期间,13 名患者发生心肌梗死,1 名患者死亡;在对照组中,1 名患者死于 MI,1 名患者死于非心脏事件。
DPR 检测到 CAC 并伴有 COPD、DM、吸烟或舒张期高血压的患者更有可能发生血管事件。因此,DPR 检测到可检测到颈动脉斑块的患者需要转介到心血管外科诊所进行进一步检查。