神经干细胞简介。

Introduction to neural stem cells.

作者信息

Kornblum Harley I

机构信息

Semel Institute and Departments of Psychiatry, Pharmacology and Pediatrics, David Geffen School of Medicine at UCLA, Los Angles, CA, USA.

出版信息

Stroke. 2007 Feb;38(2 Suppl):810-6. doi: 10.1161/01.STR.0000255757.12198.0f.

DOI:10.1161/01.STR.0000255757.12198.0f

PMID:17261745

Abstract

Neural stem cells self-renew and give rise to neurons, astrocytes and oligodendrocytes. These cells hold great promise for neural repair after injury or disease. However, a great deal of information needs to be gathered before optimally using neural stem cells for neural repair. This brief review provides an introduction to neural stem cells and briefly describes some advances in neural stem-cell biology and biotechnology.

摘要

神经干细胞能够自我更新，并分化产生神经元、星形胶质细胞和少突胶质细胞。这些细胞在损伤或疾病后的神经修复方面具有巨大潜力。然而，在将神经干细胞最佳地应用于神经修复之前，还需要收集大量信息。这篇简短的综述介绍了神经干细胞，并简要描述了神经干细胞生物学和生物技术的一些进展。