Niinikoski J, Einola S
Acta Orthop Scand. 1977;48(2):129-37. doi: 10.3109/17453677708985123.
The metabolic response of synovial tissue to surgery was investigated by synovial fluid analysis after two types of operations, medial meniscectomy and synovectomy. Analyses of intra-articular fluid were also performed in non-operated patients with traumatic effusion or chronic synovitis in the knee. It was found that the knee joint metabolism in chronic synovitis is shifted towards anaerobic glycolysis in both operated and non-operated patients whereas meniscectomized and traumatized knees are more capable of maintaining oxidative metabolism. The data also demonstrate that one of the main reasons for decreased oxygen supply on the articular surface after meniscectomies or synovectomies is excessive intra-articular effusion which, according to earlier investigations, produces pressure in the joint cavity and inhibits local capillary circulation.
通过对两种手术（内侧半月板切除术和滑膜切除术）后的滑液分析，研究了滑膜组织对手术的代谢反应。还对膝关节有创伤性积液或慢性滑膜炎的未手术患者的关节内液体进行了分析。结果发现，无论是手术患者还是未手术患者，慢性滑膜炎患者的膝关节代谢都向无氧糖酵解转变，而半月板切除和创伤后的膝关节更能维持氧化代谢。数据还表明，半月板切除术或滑膜切除术后关节表面氧气供应减少的主要原因之一是关节内积液过多，根据早期研究，这会在关节腔内产生压力并抑制局部毛细血管循环。
