Xiao Bo, Wheatley Paul S, Zhao Xuebo, Fletcher Ashleigh J, Fox Sarah, Rossi Adriano G, Megson Ian L, Bordiga S, Regli L, Thomas K Mark, Morris Russell E
EaStChem School of Chemistry, University of St. Andrews, Purdie Building, St. Andrews KY16 9ST, United Kingdom.
J Am Chem Soc. 2007 Feb 7;129(5):1203-9. doi: 10.1021/ja066098k.
Gas adsorption experiments have been carried out on a copper benzene tricarboxylate metal-organic framework material, HKUST-1. Hydrogen adsorption at 1 and 10 bar (both 77 K) gives an adsorption capacity of 11.16 mmol H2 per g of HKUST-1 (22.7 mg g(-)1, 2.27 wt %) at 1 bar and 18 mmol per g (36.28 mg g(-)1, 3.6 wt %) at 10 bar. Adsorption of D2 at 1 bar (77 K) is between 1.09 (at 1 bar) and 1.20(at <100 mbar) times the H2 values depending on the pressure, agreeing with the theoretical expectations. Gravimetric adsorption measurements of NO on HKUST-1 at 196 K (1 bar) gives a large adsorption capacity of approximately 9 mmol g(-1), which is significantly greater than any other adsorption capacity reported on a porous solid. At 298 K the adsorption capacity at 1 bar is just over 3 mmol g(-1). Infra red experiments show that the NO binds to the empty copper metal sites in HKUST-1. Chemiluminescence and platelet aggregometry experiments indicate that the amount of NO recovered on exposure of the resulting complex to water is enough to be biologically active, completely inhibiting platelet aggregation in platelet rich plasma.
已在一种苯三甲酸铜金属有机骨架材料HKUST-1上进行了气体吸附实验。在1巴和10巴（均为77K）下的氢气吸附量，在1巴时为每克HKUST-1吸附11.16毫摩尔H₂（22.7毫克克⁻¹，2.27重量%），在10巴时为每克18毫摩尔（36.28毫克克⁻¹，3.6重量%）。在1巴（77K）下D₂的吸附量根据压力在H₂值的1.09（在1巴时）至1.20（在<100毫巴时）倍之间，这与理论预期相符。在196K（1巴）下对HKUST-1上NO的重量吸附测量给出了约9毫摩尔克⁻¹的大吸附量，这明显大于在多孔固体上报道的任何其他吸附量。在298K时，1巴下的吸附量刚超过3毫摩尔克⁻¹。红外实验表明NO与HKUST-1中未占据的铜金属位点结合。化学发光和血小板聚集实验表明，将所得络合物暴露于水时回收的NO量足以具有生物活性，能完全抑制富血小板血浆中的血小板聚集。
