兔肠系膜上动脉闭塞性休克时肺组织铜锌含量的变化

Changes in pulmonary Cu-Zn contents in superior mesenteric artery occlusion shock of rabbit.

作者信息

Yan M, Ling Y L, Huang S S, Gong S Q, Xu Z X

机构信息

Department of Pathophysiology, Hebei Medical College, Shijiazhuang, PRC.

出版信息

Biol Trace Elem Res. 1991 Jun;29(3):281-8. doi: 10.1007/BF03032684.

DOI:10.1007/BF03032684

PMID:1726410

Abstract

Contents of Cu and Zn of into-pulmonary blood (IPB), out-pulmonary blood (OPB), Lung tissue, and supernatant and macrophages of Lung Lavage were determined in superior mesenteric artery occlusion (SMAO) shock of rabbits. Zn of pulmonary tissue was 11.42 +/- 0.60 and 14.52 +/- 1.78 (micrograms/g wet wt) in SMAO shock and control groups, respectively. Content of Zn was found to be lower, Cu was not changed, and Cu/Zn ratio increased in lung tissue in SMAO shock. Contents of Cu and Zn in other samples were not changed. The results suggest that lower Zn in lung tissue related to acute lung injury.

摘要

测定了兔肠系膜上动脉闭塞（SMAO）休克时肺内血（IPB）、肺外血（OPB）、肺组织以及肺灌洗上清液和巨噬细胞中的铜（Cu）和锌（Zn）含量。SMAO休克组和对照组肺组织中锌含量分别为11.42±0.60和14.52±1.78（微克/克湿重）。发现SMAO休克时肺组织中锌含量降低，铜含量未改变，铜/锌比值升高。其他样本中的铜和锌含量未改变。结果表明，肺组织中锌含量降低与急性肺损伤有关。