伤口愈合中的血管生成
Angiogenesis in wound healing.
作者信息
Arnold F, West D C
机构信息
Department of Cell and Structural Biology, University of Manchester, U.K.
出版信息
Pharmacol Ther. 1991 Dec;52(3):407-22. doi: 10.1016/0163-7258(91)90034-j.
PMID:1726477
Abstract
Angiogenesis is an essential component of wound healing. Vessel growth is controlled by the local actions of chemical mediators, the extracellular matrix, metabolic gradients, and physical forces. Manipulation of some of these factors can improve healing in experimental wounds. The clinical potential and specific application of 'angiomodulatory' strategies are discussed.
摘要
血管生成是伤口愈合的一个重要组成部分。血管生长受化学介质、细胞外基质、代谢梯度和物理力的局部作用控制。对其中一些因素的操控可改善实验性伤口的愈合情况。本文讨论了“血管调节”策略的临床潜力及具体应用。
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