Thiberville L, Salun M, Corne F, Bota S
Clinique Pneumologique, Hôpital Charles Nicolle, Centre Hospitalier et Universitaire de Rouen, 1, rue de Germont, 76031 Rouen Cedex.
Rev Mal Respir. 2006 Nov;23(5 Pt 3):16S17-16S22.
Autofluorescence endoscopy is used for more than ten years as an help to the diagnosis of bronchial precancerous lesions and early lung cancers. The technique has been extensively evaluated during the past decade including in two recent randomized studies versus conventional endoscopy that have shown an improvement for the localisation and the diagnosis of high grade precancerous lesions from 2 to 5 times. This paper reviews the principal applications and results of the use of autofluorescence endoscopy in high risk individuals, as well as innovative endoscopic approaches using the fluorescence properties of the respiratory tract.
自体荧光内镜已用于支气管癌前病变和早期肺癌的诊断十余年。在过去十年中,该技术得到了广泛评估,包括两项近期与传统内镜对比的随机研究,这些研究表明,高级别癌前病变的定位和诊断准确率提高了2至5倍。本文综述了自体荧光内镜在高危个体中的主要应用和结果,以及利用呼吸道荧光特性的创新性内镜方法。