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退伍军人与非退伍军人参与临床试验的动机及原因比较。

A comparison of veteran and nonveteran motivations and reasons for participating in clinical trials.

作者信息

Campbell Heather M, Raisch Dennis W, Sather Mike R, Warren Stuart R, Segal Alissa R

机构信息

University of New Mexico College of Pharmacy, 2502 Marble, Albuquerque, NM 87131-0001, USA.

出版信息

Mil Med. 2007 Jan;172(1):27-30. doi: 10.7205/milmed.172.1.27.

Abstract

OBJECTIVE

Knowledge of distinct motivations and reasons toward or against future trial participation is invaluable to any organization conducting trial research. Study delays often occur due to lack of recruitment. This study's primary objective was to compare veteran and nonveteran motivations and reasons.

METHODS

People in two outpatient waiting rooms were approached. The questionnaire assessed motivation toward trial involvement through use of five-point Likert-type scales and hypothetical trial scenarios; it also analyzed reasons for participation through subject ranking of reasons.

RESULTS

Veterans were more likely to participate in a trial in which all participants received the active treatment (p = 0.025). Veterans had different reasons for participation than nonveterans. Specifically, veterans felt altruism and "paying back" people who treated them were more important (p = 0.024 and p = 0.003) while financial compensation for volunteering was less important (p < 0.001).

CONCLUSIONS

Knowledge of the varying reasons for participation could potentially aid recruitment efforts.

摘要

目的

了解支持或反对未来参与试验的不同动机和原因,对于任何开展试验研究的组织来说都非常宝贵。研究延迟往往是由于招募不足导致的。本研究的主要目的是比较退伍军人和非退伍军人的动机和原因。

方法

在两个门诊候诊室接触人群。问卷通过使用五点李克特量表和假设的试验场景来评估参与试验的动机;还通过对原因进行主题排序来分析参与的原因。

结果

退伍军人更有可能参与所有参与者都接受积极治疗的试验(p = 0.025)。退伍军人参与的原因与非退伍军人不同。具体而言,退伍军人认为利他主义和“回报”治疗他们的人更重要(p = 0.024和p = 0.003),而志愿服务的经济补偿则不那么重要(p < 0.001)。

结论

了解不同的参与原因可能有助于招募工作。

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