Million Veteran Program (MVP) Coordinating Center, VA Boston Healthcare System, Boston, MA 02130, USA.
Department of Psychiatry, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Int J Environ Res Public Health. 2024 Jan 8;21(1):72. doi: 10.3390/ijerph21010072.
To address gaps in understanding the pathophysiology of Gulf War Illness (GWI), the VA Million Veteran Program (MVP) developed and implemented a survey to MVP enrollees who served in the U.S. military during the 1990-1991 Persian Gulf War (GW). Eligible Veterans were invited via mail to complete a survey assessing health conditions as well as GW-specific deployment characteristics and exposures. We evaluated the representativeness of this GW-era cohort relative to the broader population by comparing demographic, military, and health characteristics between respondents and non-respondents, as well as with all GW-era Veterans who have used Veterans Health Administration (VHA) services and the full population of U.S. GW-deployed Veterans. A total of 109,976 MVP GW-era Veterans were invited to participate and 45,270 (41%) returned a completed survey. Respondents were 84% male, 72% White, 8% Hispanic, with a mean age of 61.6 years ( = 8.5). Respondents were more likely to be older, White, married, better educated, slightly healthier, and have higher socioeconomic status than non-respondents, but reported similar medical conditions and comparable health status. Although generally similar to all GW-era Veterans using VHA services and the full population of U.S. GW Veterans, respondents included higher proportions of women and military officers, and were slightly older. In conclusion, sample characteristics of the MVP GW-era cohort can be considered generally representative of the broader GW-era Veteran population. The sample represents the largest research cohort of GW-era Veterans established to date and provides a uniquely valuable resource for conducting in-depth studies to evaluate health conditions affecting 1990-1991 GW-era Veterans.
为了弥补对海湾战争综合征(Gulf War Illness,GWI)病理生理学理解上的差距,VA 百万老兵计划(VA Million Veteran Program,MVP)开发并实施了一项针对在 1990-1991 年波斯湾战争(Gulf War,GW)期间在美国军队服役的 MVP 参与者的调查。合格的退伍军人通过邮件受邀完成一项评估健康状况以及 GW 特定部署特征和暴露情况的调查。我们通过比较受访者和非受访者、使用退伍军人健康管理局(Veterans Health Administration,VHA)服务的所有 GW 时代退伍军人以及所有 GW 部署退伍军人的人口统计、军事和健康特征,评估了这一 GW 时代队列与更广泛人群的代表性。共有 109976 名 MVP GW 时代退伍军人受邀参与,其中 45270 人(41%)完成了调查。受访者中 84%为男性,72%为白人,8%为西班牙裔,平均年龄为 61.6 岁( = 8.5)。与非受访者相比,受访者更可能年龄较大、为白人、已婚、受教育程度更高、身体稍好、社会经济地位更高,但报告的医疗状况和健康状况相似。尽管与使用 VHA 服务的所有 GW 时代退伍军人以及所有美国 GW 退伍军人总体上相似,但受访者中女性和军官的比例较高,年龄稍大。总之,MVP GW 时代队列的样本特征可被认为总体上代表了更广泛的 GW 时代退伍军人人群。该样本代表了迄今为止建立的最大的 GW 时代退伍军人研究队列,为评估影响 1990-1991 年 GW 时代退伍军人的健康状况提供了独特而有价值的资源。