兰州汉族人群17个Y染色体短串联重复序列基因座的遗传多态性
Genetic polymorphism of 17 Y-STR loci in Han Chinese living in Lanzhou.
作者信息
Sun Hong-Bing, Yang Xin, Ha Fei, Zhang Zi-Long
机构信息
Key Laboratory of Evidence of Science and Technology Research and Application, Lanzhou, 730070, China.
Forensic Science Institute of Lanzhou Public Security, Lanzhou, 730030, China.
出版信息
J Huazhong Univ Sci Technolog Med Sci. 2013 Dec;33(6):902-904. doi: 10.1007/s11596-013-1219-3. Epub 2013 Dec 13.
The genetic polymorphism across 17 Y-STR loci in a population of Han Chinese in Lanzhou was investigated. Haplotypes and allele frequencies for the 17 Y-chromosomal STRs loci DYS456, DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b, DYS393, DYS391, DYS439, DYS635, DYS392, Y GATA H4, DYS437, DYS438 and DYS448 were determined in 500 healthy unrelated autochthonous males from Lanzhou. The results showed that no shared haplotypes were observed. Gene diversity values ranged from 0.3987 (DYS391) to 0.9740 (DYS385a,b). It was concluded that these loci will be very useful for human identification in forensic cases and paternity tests within the Han Chinese population inhabiting Lanzhou.
对兰州汉族人群中17个Y-STR基因座的遗传多态性进行了研究。在来自兰州的500名健康、无亲缘关系的本地男性中，确定了17个Y染色体STR基因座DYS456、DYS389I、DYS390、DYS389II、DYS458、DYS19、DYS385a/b、DYS393、DYS391、DYS439、DYS635、DYS392、Y GATA H4、DYS437、DYS438和DYS448的单倍型及等位基因频率。结果显示未观察到共享单倍型。基因多样性值范围为0.3987（DYS391）至0.9740（DYS385a,b）。得出结论，这些基因座对于居住在兰州的汉族人群中的法医案件人类识别和亲子鉴定将非常有用。
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