Blouin A, Blouin J, Aubin P, Carter J, Goldstein C, Boyer H, Perez E
Department of Psychiatry, Ottawa Civic Hospital, Ont., Canada.
Am J Psychiatry. 1992 Jan;149(1):73-81. doi: 10.1176/ajp.149.1.73.
The aim of this research was to determine whether a seasonal pattern to symptoms of bulimia nervosa could be identified.
In study 1, seasonal patterns of binge-purge frequency and mood were compared between 31 patients with bulimia nervosa and 31 age-matched normal comparison subjects, using a modified (to include binge and purge items) version of the Seasonal Pattern Assessment Questionnaire. Study 2 involved a cross-sectional examination of binge and purge frequency and of depressive symptoms in 197 patients with bulimia nervosa assessed at various months of the year over a 4-year period.
In both the retrospective and cross-sectional studies, binge behavior was found to be highly associated with photoperiod. According to the modified Seasonal Pattern Assessment Questionnaire, purging behavior and mood also varied seasonally among patients with bulimia nervosa. However, purging behavior and severity of depression did not appear to be related to photoperiod in the cross-sectional study. The rate of seasonal affective disorder (syndromal and subsyndromal) defined by the Seasonal Pattern Assessment Questionnaire was higher among the bulimic group than the comparison subjects, but not as high as has been reported for depression in bulimia nervosa.
The results strongly support the interpretation that symptoms of bulimia nervosa primarily associated with food intake patterns are influenced by seasonal variation, and this effect may be mediated by light availability.
本研究旨在确定神经性贪食症症状是否存在季节性模式。
在研究1中,使用改良版(纳入了暴饮暴食和清除项目)的季节性模式评估问卷,比较了31名神经性贪食症患者与31名年龄匹配的正常对照受试者在暴饮暴食-清除频率和情绪方面的季节性模式。研究2对197名神经性贪食症患者在4年期间不同月份进行评估,对其暴饮暴食和清除频率以及抑郁症状进行了横断面检查。
在回顾性研究和横断面研究中,均发现暴饮暴食行为与光照周期高度相关。根据改良版季节性模式评估问卷,神经性贪食症患者的清除行为和情绪也存在季节性变化。然而,在横断面研究中,清除行为和抑郁严重程度似乎与光照周期无关。根据季节性模式评估问卷定义的季节性情感障碍(综合征性和亚综合征性)发生率在贪食症组中高于对照受试者,但不及神经性贪食症中抑郁症的报告发生率高。
结果有力地支持了以下解释,即神经性贪食症主要与食物摄入模式相关的症状受季节变化影响,且这种影响可能由光照可利用性介导。