Zipes D P
Krannert Institute of Cardiology, Department of Medicine, Indiana University School of Medicine, Indianapolis 46202.
Circulation. 1992 Jan;85(1 Suppl):I160-6.
The purpose of the present review is to suggest future approaches to the problem of sudden cardiac death. Short-term efforts should be directed toward delivering cardiopulmonary resuscitation and electrical therapy as soon as possible after the onset of an arrest. Long-term efforts encompass four interrelated, stepwise objectives that include identification of individuals at risk, mechanisms responsible for the arrhythmias, and interventions to prevent the arrhythmias. This is then followed by large-scale testing of the interventions in high-risk populations. Present funding for such research is inadequate, and the National Heart, Lung, and Blood Institute should be encouraged to consider supporting a major research initiative to combat the problem of sudden cardiac death.
本综述的目的是提出应对心源性猝死问题的未来方法。短期努力应致力于在心脏骤停发作后尽快进行心肺复苏和电治疗。长期努力包括四个相互关联的逐步目标，即识别高危个体、心律失常的发生机制以及预防心律失常的干预措施。随后应对高危人群进行大规模的干预措施测试。目前此类研究的资金不足，应鼓励美国国立心肺血液研究所考虑支持一项重大研究计划，以应对心源性猝死问题。
