Gebker Rolf, Gomaa Osama, Schnackenburg Bernhard, Rebakowski Janina, Fleck Eckart, Nagel Eike
Department of Internal Medicine - Cardiology, German Heart Institute Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
Int J Cardiovasc Imaging. 2007 Dec;23(6):747-56. doi: 10.1007/s10554-006-9204-6. Epub 2007 Feb 7.
The purpose of this study was to compare two non-contrast 2D techniques with the current contrast-enhanced MRI standard 3D technique for the routine assessment of thoracic aortic pathologies.
One hundred patients with suspected or known thoracic aortic diseases were examined with a 1.5 T scanner using 2D turbo spin echo (TSE), 2D balanced steady state free precession (balanced SSFP) and 3D contrast-enhanced MR angiography (CE-MRA). The diameters of the aorta at predefined levels were measured. The feasibility to visualize the aortic root and supra-aortic branches was tested. All morphologic abnormalities of the aorta, the aortic wall and the aortic valve, as well as image quality of TSE and balanced SSFP influencing the diagnosis were analysed.
Compared to CE-MRA, balanced SSFP and TSE allowed for the detection of a significantly higher number of relevant pathologies (thickened aortic wall and signs of emergency) in less time. No significant differences were found among the sequences for the identification of aneurysms, dissection membranes and thrombi. No single technique was able to address all clinically relevant issues. TSE was associated with a better image quality compared to balanced SSFP, which however did not translate into a significantly improved diagnostic accuracy.
The total number of pathologic findings was higher using 2D TSE and balanced SSFP when compared to 3D CE-MRA. None of the techniques applied could address all clinically relevant issues. The major drawback of TSE is its relatively long scanning time while balanced SSFP is associated with more artifacts.
本研究旨在比较两种非增强二维技术与当前用于胸主动脉病变常规评估的增强磁共振成像标准三维技术。
对100例疑似或已知胸主动脉疾病的患者使用1.5T扫描仪进行二维快速自旋回波(TSE)、二维稳态自由进动(平衡SSFP)和三维对比增强磁共振血管造影(CE-MRA)检查。测量主动脉在预定水平的直径。测试可视化主动脉根部和主动脉弓上分支的可行性。分析主动脉、主动脉壁和主动脉瓣的所有形态学异常,以及影响诊断的TSE和平衡SSFP的图像质量。
与CE-MRA相比,平衡SSFP和TSE能在更短时间内检测到显著更多的相关病变(主动脉壁增厚和急症迹象)。在识别动脉瘤、夹层膜和血栓的序列之间未发现显著差异。没有单一技术能够解决所有临床相关问题。与平衡SSFP相比,TSE的图像质量更好,但这并未转化为显著提高的诊断准确性。
与三维CE-MRA相比,使用二维TSE和平衡SSFP时病理发现的总数更高。所应用的技术均不能解决所有临床相关问题。TSE的主要缺点是扫描时间相对较长,而平衡SSFP则伴有更多伪影。