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使用非增强磁共振血管造影评估胸主动脉尺寸和病变的简化快速方案

Simplified Rapid Protocol for Assessing the Thoracic Aortic Dimensions and Pathology with Noncontrast MR Angiography.

作者信息

Verma Megha, Yarlagadda Bharath, Hendrani Aditya, Bhat Ambarish P, Kumar Senthil

机构信息

Division of College of Arts and Sciences, Saint Louis University, St. Louis, Missouri.

Division of Cardiology, Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico.

出版信息

Int J Angiol. 2019 Jun;28(2):130-136. doi: 10.1055/s-0039-1688473. Epub 2019 May 11.

Abstract

Contrast enhanced magnetic resonance angiography (CE-MRA) is limited by long acquisition time and contrast exposure in aortic emergencies. To compare the effcacy of dark blood (DB) and bright blood (BB) noncontrast sequences with the gold standard CE-MRA using a novel protocol for performing consistent thoracic aortic measurements and thoracic aortic pathologies identifications. A total of 66 patients with suspected or known thoracic aortic pathology who underwent CE-MRA underwent DB and BB imaging prior to CE-MRA for planning purposes. Aortic dimension was measured at 10 standard reference points in the ascending, arch, and descending aorta. Detection of aortic pathologies was recorded individually for each noncontrast sequence. When comparing the CE-MRA to the DB images and CE-MRA to the BB images, a majority of the measurement differences were less than or equal to 2 mm or resulted in no change of diagnostic class (95% for CE-MRA vs. DB and 96% for CE-MRA vs. BB). Of the patients who had major changes in diagnostic class (e.g., changes in two or three classes), the absolute measurements were not clinically significant in any given patient to warrant a change in management. Individually, the DB and BB sequences allowed for accurate recognition of all 47 aortic pathologies. DB and BB sequences produced comparable and consistent measurements of the thoracic aorta when compared with CE-MRA. In a situation where CE-MRA is not readily available or contraindicated, noncontrast MRA using our protocol is a reliable alternative to CE-MRA for assessment of aortic pathologies.

摘要

对比增强磁共振血管造影(CE-MRA)在主动脉急症中受限于较长的采集时间和对比剂暴露。为了使用一种用于进行一致的胸主动脉测量和胸主动脉病变识别的新方案,比较黑血(DB)和亮血(BB)非对比序列与金标准CE-MRA的有效性。共有66例疑似或已知胸主动脉病变且接受了CE-MRA检查的患者,在进行CE-MRA之前,为了规划目的先进行了DB和BB成像。在升主动脉、主动脉弓和降主动脉的10个标准参考点测量主动脉尺寸。针对每个非对比序列分别记录主动脉病变的检测情况。将CE-MRA与DB图像以及CE-MRA与BB图像进行比较时,大多数测量差异小于或等于2毫米,或者诊断类别没有变化(CE-MRA与DB相比为95%,CE-MRA与BB相比为96%)。在诊断类别有重大变化的患者中(例如,变化两个或三个类别),任何特定患者的绝对测量值在临床上都不具有显著意义,不足以导致管理方式的改变。单独来看,DB和BB序列能够准确识别所有47种主动脉病变。与CE-MRA相比,DB和BB序列对胸主动脉的测量具有可比性和一致性。在无法轻易获得CE-MRA或其为禁忌的情况下,使用我们的方案进行非对比MRA是评估主动脉病变的一种可靠替代方法,可替代CE-MRA。

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