Wender Paul A, Longcore Kate E
Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA.
Org Lett. 2007 Feb 15;9(4):691-4. doi: 10.1021/ol0630245.
The isolation, characterization, and preliminary biological activity of apoptolidin D, a new apoptolidin that exhibits anti-proliferative activity against H292 human lung carcinoma cells at nanomolar concentrations, are reported. Its equilibration with isoapoptolidin D and characterization of the latter are also described. [structure: see text].
报道了一种新的凋亡素——凋亡素D的分离、表征及其初步生物活性，该凋亡素在纳摩尔浓度下对H292人肺癌细胞具有抗增殖活性。还描述了它与异凋亡素D的平衡以及后者的表征。[结构：见正文]
