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起源于右心耳的局灶性房性心动过速:心电图和电生理特征及射频消融

Focal atrial tachycardias arising from the right atrial appendage: electrocardiographic and electrophysiologic characteristics and radiofrequency ablation.

作者信息

Roberts-Thomson Kurt C, Kistler Peter M, Haqqani Haris M, McGavigan Andrew D, Hillock Richard J, Stevenson Irene H, Morton Joseph B, Vohra Jitendra K, Sparks Paul B, Kalman Jonathan M

机构信息

Department of Cardiology, Royal Melbourne Hospital, Melbourne, Australia.

出版信息

J Cardiovasc Electrophysiol. 2007 Apr;18(4):367-72. doi: 10.1111/j.1540-8167.2006.00754.x. Epub 2007 Feb 7.

Abstract

OBJECTIVE

To characterize the electrocardiographic and electrophysiological features and frequency of focal atrial tachycardia (AT) originating from the right atrial appendage (RAA).

BACKGROUND

The RAA has been described as a site of origin of AT, but detailed characterization of these tachycardias is limited.

METHODS

Ten patients (3.8%) of 261 undergoing radiofrequency ablation (RFA) for focal AT are reported. Endocardial activation maps (EAM) were recorded from catheters at the CS (10 pole), tricuspid annulus (20 pole Halo catheter), and His positions. P waves were classified as negative, positive, isoelectric, or biphasic.

RESULTS

The mean age was 39 +/- 20 years, nine males, with symptoms for 4.1 +/- 5.1 years. Tachycardia was incessant in seven patients, spontaneous in one patient, and induced by programmed extrastimuli in two patients. These foci had a characteristic P wave morphology. The P wave was negative in lead V(1) in all patients, becoming progressively positive across the precordial leads. The P waves in the inferior leads were low amplitude positive in the majority of patients. Earliest EAM activity occurred on the Halo catheter in all patients. Mean activation time at the successful RFA site =-38 +/- 15 msec. Irrigated catheters were used in six patients, due to difficulty achieving adequate power. RFA was acutely successful in all patients. Long-term success was achieved in all patients over a mean follow up of 8 +/- 7 months.

CONCLUSIONS

The RAA is an uncommon site of origin for focal AT (3.8%). It can be suspected as a potential anatomic site of AT origin from the characteristic P wave and activation timing. Irrigated ablation catheters are often required for successful ablation. Long-term success was achieved with focal ablation in all patients.

摘要

目的

描述起源于右心耳(RAA)的局灶性房性心动过速(AT)的心电图和电生理特征及发生率。

背景

RAA已被描述为AT的起源部位,但对这些心动过速的详细特征描述有限。

方法

报告了261例行局灶性AT射频消融(RFA)的患者中的10例(3.8%)。通过放置在冠状窦(10极)、三尖瓣环(20极Halo导管)和希氏束部位的导管记录心内膜激动标测图(EAM)。P波被分类为负向、正向、等电位或双向。

结果

平均年龄为39±20岁,9例男性,症状持续4.1±5.1年。7例患者的心动过速为持续性,1例为自发性,2例由程控期外刺激诱发。这些病灶具有特征性的P波形态。所有患者V1导联的P波均为负向,胸前导联逐渐转为正向。大多数患者下壁导联的P波为低振幅正向。所有患者最早的EAM活动均出现在Halo导管上。成功RFA部位的平均激动时间=-38±15毫秒。6例患者因难以获得足够功率而使用了灌注射频导管。所有患者的RFA即刻成功。平均随访8±7个月,所有患者均获得长期成功。

结论

RAA是局灶性AT的罕见起源部位(3.8%)。根据特征性P波和激动时间,可怀疑其为AT起源的潜在解剖部位。成功消融通常需要使用灌注射频导管。所有患者通过局灶性消融均获得长期成功。

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