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压力性尿失禁手术疗效欠佳患者的治疗选择

Treatment options for patients with suboptimal response to surgery for stress urinary incontinence.

作者信息

Appell Rodney A, Davila G Willy

机构信息

Baylor College of Medicine, Houston, TX 77030, USA.

出版信息

Curr Med Res Opin. 2007 Feb;23(2):285-92. doi: 10.1185/030079906X162845.

Abstract

BACKGROUND

Many women with stress urinary incontinence (SUI) undergo surgery to relieve their symptoms. Currently, tension-free vaginal tape or transobturator tape sling procedures are the surgical treatments of choice. Although these procedures are often successful, a growing number of women experience suboptimal results ranging from improvement without cure to postoperative failure. Follow-up surgery often improves residual or recurrent symptoms but generally carries lower success rates and higher complication risks. Additionally, many women with suboptimal results are reluctant to undergo further surgery.

SCOPE

A PubMed literature search for studies of SUI treatment options published from 1986 to 2006 was performed.

FINDINGS

The literature revealed a gap in published studies addressing non-surgical options for patients with failed SUI surgeries. Studies of non-surgical treatments for SUI often exclude women who have had prior surgeries, or do not analyze this subgroup. It is, therefore, difficult to assess non-surgical treatment options for women with failed surgeries. Women whose residual or recurring SUI is attributable to intrinsic sphincter deficiency may instead elect the injection of a bulking agent. Bulking agents are associated with a low rate of complications but frequently require several injections to be successful. Women experiencing suboptimal surgical results whose SUI is attributable to hypermobility may select a new non-surgical treatment, radiofrequency collagen denaturation. This non-invasive procedure has also demonstrated a low rate of complications.

CONCLUSIONS

Considering the effect of SUI symptoms on women's quality of life, and with more women experiencing suboptimal results after surgery for SUI, it is important to assess alternatives to further surgery.

摘要

背景

许多压力性尿失禁(SUI)女性会接受手术以缓解症状。目前,无张力阴道吊带术或经闭孔吊带术是首选的外科治疗方法。尽管这些手术通常很成功,但越来越多的女性治疗效果欠佳,从症状改善但未治愈到术后失败不等。后续手术通常能改善残留或复发症状,但总体成功率较低且并发症风险较高。此外,许多治疗效果欠佳的女性不愿接受进一步手术。

范围

对1986年至2006年发表的关于SUI治疗选择的研究进行了PubMed文献检索。

结果

文献显示,已发表的研究在针对SUI手术失败患者的非手术选择方面存在空白。SUI非手术治疗的研究通常排除了既往接受过手术的女性,或未对该亚组进行分析。因此,很难评估手术失败女性的非手术治疗选择。残余或复发性SUI归因于内在括约肌缺陷的女性可选择注射填充剂。填充剂并发症发生率低,但通常需要多次注射才能成功。手术效果欠佳且SUI归因于尿道过度活动的女性可选择一种新的非手术治疗方法——射频胶原变性术。这种非侵入性手术并发症发生率也很低。

结论

考虑到SUI症状对女性生活质量的影响,以及越来越多的女性在SUI手术后效果欠佳,评估进一步手术的替代方案很重要。

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