Morrow J D
Vanderbilt University Medical Center, Pharmacy and Therapeutics Committee, Vanderbilt University, Nashville.
Am J Med Sci. 1992 Jan;303(1):35-9. doi: 10.1097/00000441-199201000-00008.
There are currently six cephalosporins available in the United States for oral use. These agents possess a wide spectrum of activity, are relatively safe to use, and are effective for certain infections involving the respiratory tract, skin, and urinary tract. Nonetheless, in general, they offer no advantage over other classes of antimicrobial drugs and are far more expensive. As a result, the oral cephalosporins are not agents of first choice for the treatment of infection but should be reserved for use as alternative therapy.
目前在美国有六种口服头孢菌素可供使用。这些药物具有广泛的活性谱,使用相对安全,对某些涉及呼吸道、皮肤和泌尿道的感染有效。然而,总体而言,它们与其他类别的抗菌药物相比没有优势,而且价格要昂贵得多。因此,口服头孢菌素不是治疗感染的首选药物,而应留作替代疗法使用。