Cereda Emanuele, Limonta Daniela, Pusani Chiara, Vanotti Alfredo
Servizio di Nutrizione Clinica e Dietetica, ASL Como, Como, Italy.
Gerontology. 2007;53(4):184-6. doi: 10.1159/000099468. Epub 2007 Feb 9.
The Geriatric Nutritional Risk Index (GNRI) is a new index recently introduced for predicting risk of nutritional-related complications in elderly patients. It combines albumin with information about body weight: GNRI = (1.489 x albumin, g/l) + (41.7 x present/ideal body weight), with ideal weight calculated according to the Lorentz formula. Because standing height (SH) is frequently difficult to obtain in older people, in Lorentz equations this parameter has been replaced by estimated height (EH) from knee height. Though, if EH is well accepted as a valid surrogate for SH, the same might not be expected for its use in ideal body weight calculation, with possible consequences in grading nutritional risk correctly.
The aim of this study was to investigate whether the use of SH rather than EH for the calculation of ideal body weight predicts similar outcomes by GNRI.
Body weight, SH and EH were obtained in 231 long-term care resident elderly (88 males and 143 females, mean age +/- SD 80.0 +/- 8.4, range 65-97 years). Blood samples were assessed for albumin concentration. Ideal body weight was derived from the Lorentz formula using both SH and EH. According to both ideal weight estimates, nutritional risk was defined by the GNRI score.
The Pearson correlation coefficients were high for both EH (with SH; r = 0.90) and estimates of ideal body weight (r = 0.90) and all were highly significant (p < 0.0001). A statistically significant difference was found between SH and EH (p = 0.0265). Similar and expectable differences in significance have also been observed between ideal body weights (p = 0.0271). However, an accordance of 95.2% has been detected (Kendall's tau test: tau = 0.85, p < 0.0001) in grading nutritional risk by GNRI.
The use of EH for ideal body weight calculation and nutritional risk assessment by GNRI is feasible. Thus, GNRI seems to have been designed in the best way and its use is really attractive, particularly when considering the low-grade participation demanded of the patient in the assessment. This simple and valid assessment tool should be taken into greater consideration.
老年营养风险指数(GNRI)是最近推出的一种用于预测老年患者营养相关并发症风险的新指数。它将白蛋白与体重信息相结合:GNRI =(1.489×白蛋白,g/l)+(41.7×实际体重/理想体重),理想体重根据洛伦兹公式计算。由于老年人常常难以测量身高,在洛伦兹公式中该参数已被根据膝高估算的身高(EH)所取代。然而,如果认为EH可作为身高(SH)的有效替代指标,其在理想体重计算中的应用可能并非如此,这可能会对正确分级营养风险产生影响。
本研究旨在调查使用SH而非EH计算理想体重时,GNRI预测的结果是否相似。
获取了231名长期护理机构老年居民(88名男性和143名女性,平均年龄±标准差80.0±8.4岁,范围65 - 97岁)的体重、SH和EH。对血样进行白蛋白浓度检测。分别使用SH和EH按照洛伦兹公式计算理想体重。根据两种理想体重估算值,通过GNRI评分定义营养风险。
EH与SH的皮尔逊相关系数较高(r = 0.90),理想体重估算值之间的相关系数也较高(r = 0.90),且均具有高度显著性(p < 0.0001)。SH与EH之间存在统计学显著差异(p = 0.0265)。理想体重之间也观察到了类似且预期的显著性差异(p = 0.0271)。然而,在通过GNRI分级营养风险时,一致性达到了95.2%(肯德尔tau检验:tau = 0.85,p < 0.0001)。
使用EH计算理想体重并通过GNRI进行营养风险评估是可行的。因此,GNRI似乎设计得较为合理,其应用确实具有吸引力,尤其是考虑到评估过程中患者所需的低程度参与。这种简单有效的评估工具应得到更多关注。