Cohn D E, Resnick K E, Eaton L A, deHart J, Zanagnolo V
Departments of Obstetrics and Gynecology, Division of Gynecologic Oncology, The Ohio State University College of Medicine, 320 West 10th Avenue, Columbus, OH 43210, USA.
Int J Gynecol Cancer. 2007 Jan-Feb;17(1):274-9. doi: 10.1111/j.1525-1438.2006.00747.x.
Although in the past two decades there has been a sharp rise in the incidence of extranodal primary lymphomas in the United States, non-Hodgkin's lymphoma (NHL) of the female genital tract is still rare. We present four cases of extranodal NHL presenting with signs and symptoms consistent with cancer of the vagina or cervix and lacking the "B" symptoms often associated with systemic lymphoma such as fever, weight loss, night sweat, and fatigue. It is important for gynecologists to be aware of this neoplastic disease and to include cervical or vaginal lymphoma in the differential diagnosis of patients presenting with examinations suggestive of cervical or vaginal cancer. A correct diagnosis leads to the appropriate therapy, and radical gynecological surgery can be avoided for primary cervical and vaginal lymphoma.
尽管在过去二十年中美国结外原发性淋巴瘤的发病率急剧上升，但女性生殖道非霍奇金淋巴瘤（NHL）仍然罕见。我们报告了4例结外NHL病例，这些病例表现出与阴道或宫颈癌一致的体征和症状，且没有通常与全身性淋巴瘤相关的“B症状”，如发热、体重减轻、盗汗和疲劳。妇科医生必须意识到这种肿瘤性疾病，并将宫颈或阴道淋巴瘤纳入表现出提示宫颈癌或阴道癌检查结果的患者的鉴别诊断中。正确的诊断有助于采取适当的治疗方法，对于原发性宫颈和阴道淋巴瘤可避免进行根治性妇科手术。
