Marmash R W, Dalwai A K, Szucs G, Molla A M, Pacsa A S, Al-Nakib W, Albert M J
Department of Microbiology, Kuwait University, Kuwait.
Epidemiol Infect. 2007 Nov;135(8):1331-7. doi: 10.1017/S0950268807007868. Epub 2007 Feb 12.
There are no data on the serotypes of rotaviruses prevalent in Kuwait, which has a large expatriate population and hence a focal point for transmission of pathogens. The serotype information will contribute to the fund of knowledge on the world epidemiology of rotavirus serotypes and will predict the outcome of vaccination in Kuwait. Of the 75 rotavirus-positive samples from 172 children (aged <5 years) with severe diarrhoea, 69 were genotyped. The distribution of genotypes was G1 (63.8%) followed by G9 (10.2%), G2 (7.3%), G4 (7.3%) and G3 (4.4%). Among the P types, P[8] was the most common type found across all G types. By fluorescent focus neutralization test, serum antibodies to genotypes G1 (94%), G4 (68%) and G9 (46%) were found in 120 other children. These results show that G1 is the predominant serotype in Kuwait and that a vaccine that contains G1 will be most effective.
科威特没有关于轮状病毒流行血清型的数据，该国拥有大量外籍人口，因此是病原体传播的一个焦点。血清型信息将有助于丰富关于轮状病毒血清型世界流行病学的知识储备，并能预测科威特的疫苗接种效果。在172名重度腹泻的5岁以下儿童的75份轮状病毒阳性样本中，69份进行了基因分型。基因型分布为G1（63.8%），其次是G9（10.2%）、G2（7.3%）、G4（7.3%）和G3（4.4%）。在P型中，P[8]是在所有G型中最常见的类型。通过荧光灶中和试验，在另外120名儿童中发现了针对G1（94%）、G4（68%）和G9（46%）基因型的血清抗体。这些结果表明，G1是科威特的主要血清型，包含G1的疫苗将最有效。
