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采用电热原子吸收光谱法(ETAAS)和电感耦合等离子体发射光谱法(ICP-OES)测定阿根廷草药中的重金属以进行质量控制。

Determination of heavy metals for the quality control in Argentinian herbal medicines by ETAAS and ICP-OES.

作者信息

Gomez María R, Cerutti Soledad, Sombra Lorena L, Silva María F, Martínez Luis D

机构信息

Universidad Nacional de San Luis, Facultad de Química, Bioquímica y Farmacia, Chacabuco y Pedernera, 5700 San Luis, Argentina.

出版信息

Food Chem Toxicol. 2007 Jun;45(6):1060-4. doi: 10.1016/j.fct.2006.12.013. Epub 2006 Dec 30.

DOI:10.1016/j.fct.2006.12.013
PMID:17291663
Abstract

The determination of trace elements in Hypericum perforatum leaves and flowers, their teas, tinctures and tablets was carried out by Electrothermal Atomic Absorption Spectrometry (ETAAS) and Ultrasonic Nebulization System coupled to Inductively Coupled Plasma Optical Emission Spectrometry (USN-ICP-OES). Hypericum perforatum (St. John's wort), is a phytomedicine used for the treatment of depression. Samples were collected from different sources in the argentinian market. Heavy metals contents in the investigated samples were found at different levels. Chromium and cobalt were undetectable above their limits of detection in both liquid and solid samples; while aluminum, cadmium, lead, iron and vanadium were present in the majority of samples. The analytical results obtained for all metals indicate that they were present at concentration well below the acceptable daily intake recommended by the World Health Organization. Based on the results obtained in the present work, it is concluded that the present techniques are suitable for the routine determination of heavy metals concentration in phytopharmaceuticals.

摘要

采用电热原子吸收光谱法(ETAAS)以及与电感耦合等离子体发射光谱仪联用的超声雾化系统(USN-ICP-OES),对贯叶连翘的叶、花、其茶剂、酊剂和片剂中的微量元素进行了测定。贯叶连翘是一种用于治疗抑郁症的植物药。样品取自阿根廷市场的不同来源。在所研究的样品中,重金属含量处于不同水平。在液体和固体样品中,铬和钴均未检出,其含量高于检测限;而大多数样品中存在铝、镉、铅、铁和钒。所有金属的分析结果表明,它们的浓度远低于世界卫生组织建议的每日可接受摄入量。基于本研究获得的结果,得出结论:目前的技术适用于植物药中重金属浓度的常规测定。

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