Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, 75 DeKalb Avenue, Brooklyn, NY 11201, USA.
Phytochem Anal. 2011 May-Jun;22(3):189-98. doi: 10.1002/pca.1287. Epub 2011 Feb 21.
It is estimated that about 70-80% of the world's population relies on non-conventional medicine, mainly of herbal origin. However, owing to the nature and sources of herbal medicines, they are sometimes contaminated with toxic heavy metals such as lead, arsenic, mercury and cadmium, which impose serious health risks to consumers. It is critical to analyse source materials for heavy metals in order to ensure that their concentrations meet the related standards or regulations limiting their concentrations in herbal medicines. In this review, different analytical methods for analysis of heavy metals in herbal medicines are discussed.
To provide a comprehensive review of the current state of the art in analytical methods used to detect heavy metals in herbal medicines.
We systematically searched and reviewed the research articles regarding analytical methods for heavy metals in herbal medicine from various databases, such as Medline/PubMed, ScienceDirect, SciFinder, Google Scholar, EBSCO, Gale InfoTrac, Ingenta, Ovid, ProQuest and ISI Web of Knowledge.
In this review, we discuss in detail several commonly used and sensitive analytical techniques, including atomic absorption spectrometry, inductively coupled plasma optical emission spectrometry or mass spectrometry, X-ray fluorescence spectrometry, high-performance liquid chromatography, differential pulse polarography, neutron activation analysis and anodic stripping voltammetry. We also provide some application examples of these analytical techniques for heavy metals in herbal medicines.
据估计，全世界约有 70-80%的人口依赖于非传统药物，主要是草药。然而，由于草药的性质和来源，它们有时会受到有毒重金属如铅、砷、汞和镉的污染，这对消费者的健康构成了严重威胁。分析重金属的来源材料对于确保其浓度符合相关标准或法规限制草药中重金属的浓度至关重要。在本综述中，讨论了用于分析草药中重金属的不同分析方法。
提供草药中重金属分析方法的最新技术综述。
我们系统地搜索和审查了来自各种数据库的关于草药中重金属分析方法的研究文章，如 Medline/PubMed、ScienceDirect、SciFinder、Google Scholar、EBSCO、Gale InfoTrac、Ingenta、Ovid、ProQuest 和 ISI Web of Knowledge。
在本综述中，我们详细讨论了几种常用且敏感的分析技术，包括原子吸收光谱法、电感耦合等离子体发射光谱法或质谱法、X 射线荧光光谱法、高效液相色谱法、差动脉冲极谱法、中子活化分析和阳极溶出伏安法。我们还提供了这些分析技术在草药中重金属分析方面的一些应用实例。
