促肾上腺皮质激素对幼鼠大脑代谢作用的某些方面。
Some aspects of ACTH action on cerebral metabolism in infant rats.
作者信息
Ardeleanu A, Sterescu N
出版信息
Physiologie. 1975;12(1):31-5.
PMID:172923
Abstract
In 150 newborn rats of either sex the influence of ACTH on cerebral phospholipid, phosphoprotein, and nucleic acids metabolism was investigated. The results show that ACTH induces a great stimulation of the cerebral phospholipid metabolism, especially in 14-and 21-day-old rats, a significant increase in the phosphoprotein metabolism at 7 and 14 days after birth, and a stimulation of the RNA synthesis in 7- and 14-day-old rats. The significance of these results is discussed.
摘要
在150只新生雌雄大鼠中，研究了促肾上腺皮质激素（ACTH）对脑磷脂、磷蛋白和核酸代谢的影响。结果表明，ACTH能极大地刺激脑磷脂代谢，尤其是在14日龄和21日龄的大鼠中；在出生后7天和14天，磷蛋白代谢显著增加；在7日龄和14日龄的大鼠中，RNA合成受到刺激。文中对这些结果的意义进行了讨论。
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