边缘型人格障碍与双相谱系障碍之间的关联
The interface between borderline personality disorder and bipolar spectrum disorders.
作者信息
Paris Joel, Gunderson John, Weinberg Igor
机构信息
Department of Psychiatry, Institute of Community and Family Psychiatry, SMBD-Jewish General Hospital, McGill University, Montreal, Québec, Canada H3T 1E4.
出版信息
Compr Psychiatry. 2007 Mar-Apr;48(2):145-54. doi: 10.1016/j.comppsych.2006.10.001. Epub 2007 Jan 2.
OBJECTIVE
This review examines whether borderline personality disorder (BPD) should be considered part of the bipolar spectrum.
METHODS
A literature review examined studies of co-occurrence, phenomenology, family prevalence, medication response, longitudinal course, and etiology.
RESULTS
Borderline personality disorder and bipolar disorder co-occur, but their relationship is not consistent or specific. There are overlaps but important differences in phenomenology and in medication response. Family studies suggest clear distinctions, and it is unusual for BPD to evolve into bipolar disorder. Research is insufficient to establish whether these disorders have a common etiology.
CONCLUSIONS
Existing data fail to support the conclusion that BPD and bipolar disorders exist on a spectrum but allows for the possibility of partially overlapping etiologies.
目的
本综述探讨边缘型人格障碍（BPD）是否应被视为双相谱系的一部分。
方法
通过文献综述对共病、现象学、家族患病率、药物反应、病程及病因等方面的研究进行考察。
结果
边缘型人格障碍与双相情感障碍共病，但二者关系并不一致或具有特异性。在现象学及药物反应方面存在重叠但也有重要差异。家族研究表明二者有明显区别，BPD演变为双相情感障碍的情况并不常见。目前研究不足以确定这些障碍是否具有共同病因。
结论
现有数据无法支持BPD与双相情感障碍属于同一谱系的结论，但允许二者病因部分重叠的可能性存在。
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