Marchal G, Michiels J, Bosmans H, Van Hecke P
Department of Radiology, University Hospitals K.U. Leuven, Belgium.
J Comput Assist Tomogr. 1992 Jan-Feb;16(1):25-9. doi: 10.1097/00004728-199201000-00005.
Most sequences for MR angiography (MRA) used today exploit the macroscopic motion of the blood to differentiate vessels from the stationary tissues. An alternative approach to inflow based MRA is contrast enhanced MRA, in which relaxation agents are used to selectively shorten the T1 of the blood below the T1 value of the stationary tissues. We have evaluated cerebral Gd enhanced MRA, comparing it with conventional angiography and noncontrast inflow based MRA. Contrast/enhanced MRAs were obtained at 1.0 T with a 3D FISP sequence with TR/TE/alpha: 35-40 ms, 7-11 ms/TE/25 degrees. Contrast enhancement was obtained by a biphasic injection of a double dose of Gd-DOTA (0.2 mmol/kg) during image acquisition. With the described technique the conspicuity of both cerebral arteries and veins is improved compared to nonenhanced inflow MRA.
如今使用的大多数磁共振血管造影（MRA）序列都是利用血液的宏观运动来区分血管和静止组织。基于流入的MRA的一种替代方法是对比增强MRA，其中使用弛豫剂选择性地将血液的T1缩短至低于静止组织的T1值。我们评估了脑钆增强MRA，并将其与传统血管造影和基于非对比流入的MRA进行了比较。在1.0 T下使用3D FISP序列（TR/TE/α：35 - 40 ms，7 - 11 ms/TE/25°）获得对比增强MRA。在图像采集期间通过双相注射双倍剂量的钆喷酸葡胺（0.2 mmol/kg）来实现对比增强。与未增强的流入MRA相比，使用所述技术可提高脑动脉和静脉的显影度。
