Rafeiner P
Medizinische Poliklinik, Universitätsspital Basel.
Praxis (Bern 1994). 2007 Jan 24;96(4):101-6. doi: 10.1024/1661-8157.96.4.101.
Osteoporosis belongs to the ten most common diseases. There is no doubt about the importance of primary prophylaxis. Regarding postmenopausal women the following subjects will be discussed: How can the fracture risk be evaluated? What kind of pharmacotherapy is available? An osteodensitometry will be performed if risk factors are present. Most of the laboratory testing can be done in a primary care unit to exclude secondary forms of osteoporosis. Guidelines concerning the decision to start a therapy are based on the individual risk profile and on the osteodensitometric score. The pharmacotherapy with bisphosphonates, selective estrogen receptor modulators and parathormone will be discussed. Strontiumranelate is a very promising medicine and will soon be available in Switzerland.
骨质疏松症属于十大常见疾病。毫无疑问，一级预防至关重要。对于绝经后女性，将讨论以下主题：如何评估骨折风险？有哪些可用的药物治疗方法？如果存在风险因素，将进行骨密度测定。大多数实验室检测可在基层医疗单位进行，以排除继发性骨质疏松症。关于开始治疗的决策指南基于个体风险状况和骨密度评分。将讨论双膦酸盐、选择性雌激素受体调节剂和甲状旁腺激素的药物治疗。雷奈酸锶是一种非常有前景的药物，很快将在瑞士上市。
