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[男性压力性尿失禁的既定治疗方案]

[Established treatment options for male stress urinary incontinence].

作者信息

Hampel C, Gillitzer R, Wiesner C, Thüroff J W

机构信息

Urologische Klinik und Poliklinik, Johannes-Gutenberg-Universität, Langenbeckstrasse 1, 55131, Mainz, Deutschland.

出版信息

Urologe A. 2007 Mar;46(3):244-8, 250-6. doi: 10.1007/s00120-007-1304-y.

Abstract

Nowadays, male stress urinary incontinence is rare and almost always of iatrogenic origin (radiotherapy, pelvic surgery). However, the prognosis of urinary incontinence following surgery is good and can be improved by pelvic floor muscle exercises in combination with biofeedback systems. For the remaining patient cohort with persistent urinary incontinence, several established surgical treatment options are available. Suburothelial injections of bulking agents can easily be performed in an ambulatory setting. However, regardless of the material used, long-term results are disappointing. Moreover, the residual urethral function deteriorates due to cicatrization of the suburothelial plexus with consequent loss of urethral elasticity. The fascial sling procedure in males has to be performed in preoperated areas and is as technically demanding for the surgeon as it is burdening for the patient. Alloplastic material is not used, thus minimizing risks for arrosion or infection. Since the sling tension can neither be standardized nor postoperatively readjusted, the risk of overcorrection is considerable and the success of the procedure is heavily dependent on the surgeon's experience. Despite wear and high revision rates, the technically mature artificial sphincter produces excellent continence results and has become the gold standard in the therapy of male stress urinary incontinence. The circumferential and continuous urethral compression by the cuff is highly effective, but at the price of an almost inevitable urethral atrophy. To overcome this problem, various surgical techniques have been developed (tandem cuff, cuff downsizing, transcorporal cuff placement). However, the expensive artificial sphincter is not a nostrum for every incontinent man, since it requires certain minimal cognitive and manual capabilities. Therefore, the search for less demanding treatment alternatives seems to be necessary, even if one has to accept lower continence rates.

摘要

如今,男性压力性尿失禁较为罕见,几乎均为医源性病因(放疗、盆腔手术)。然而,手术后尿失禁的预后良好,盆底肌肉锻炼结合生物反馈系统可改善预后。对于其余仍存在持续性尿失禁的患者群体,有几种既定的手术治疗方案可供选择。在门诊环境中即可轻松进行尿道下注射填充剂。然而,无论使用何种材料,长期效果都不尽人意。此外,尿道下丛的瘢痕化会导致尿道弹性丧失,进而使残余尿道功能恶化。男性的筋膜吊带手术必须在先前手术过的区域进行,对手术医生来说技术要求高,对患者来说负担也重。不使用异体材料,从而将腐蚀或感染风险降至最低。由于吊带张力既无法标准化,术后也无法重新调整,过度矫正的风险相当大,手术的成功率很大程度上取决于手术医生的经验。尽管人工括约肌存在磨损且翻修率高,但技术成熟的人工括约肌能产生极佳的控尿效果,已成为男性压力性尿失禁治疗的金标准。袖带对尿道进行环形连续压迫非常有效,但代价是几乎不可避免地会出现尿道萎缩。为克服这一问题,已开发出各种手术技术(串联袖带、袖带缩小、经体部袖带放置)。然而,昂贵的人工括约肌并非适用于每一位尿失禁男性,因为它需要一定的最低认知和手动能力。因此,即便不得不接受较低的控尿率,寻找要求较低的治疗替代方案似乎仍有必要。

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