Ramdall Risha B, Alasio Teresa M, Cai Guoping, Yang Grace C H
Department of Pathology, New York University School of Medicine, New York, NY 10016, USA.
Diagn Cytopathol. 2007 Mar;35(3):137-42. doi: 10.1002/dc.20568.
We report the fine-needle aspiration (FNA) biopsy diagnosis of two rare cases of primary vascular neoplasms unique to the spleen: a littoral cell angioma from a 31-yr-old Caucasian woman and a splenic hamartoma from a 46-yr-old black man. The cytologic features of splenic hamartoma and of littoral cell angioma of the spleen were described three times in cytologic literature: two were bench-top aspirates and one was FNA biopsy thought to be metastatic carcinoma. To the best of our knowledge, the current two cases were the first diagnosed by FNA biopsy. Our approach to the FNA biopsy diagnosis of these rare vascular neoplasms via compact cell block and immunohistochemistry is described. The differential diagnosis with other primary vascular splenic neoplasms is also discussed.
我们报告了两例罕见的脾脏原发性血管肿瘤的细针穿刺抽吸（FNA）活检诊断：一例是来自一名31岁白人女性的边缘细胞血管瘤，另一例是来自一名46岁黑人男性的脾脏错构瘤。脾脏错构瘤和脾脏边缘细胞血管瘤的细胞学特征在细胞学文献中已有三次描述：两次是台式抽吸物，一次是被认为是转移性癌的FNA活检。据我们所知，目前这两例是首例通过FNA活检诊断的病例。本文描述了我们通过致密细胞块和免疫组织化学对这些罕见血管肿瘤进行FNA活检诊断的方法。还讨论了与其他原发性脾脏血管肿瘤的鉴别诊断。
