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儿童脾性边缘细胞血管瘤1例罕见病例。

A rare case of splenic littoral cell angioma in a child.

作者信息

Bedir Recep, Sehitoǧlu Ibrahim, Calapoǧlu Ahmet Salih, Yurdakul Cüneyt

机构信息

Department of Pathology, Recep Tayyip Erdogan University of Medical Faculty, Rize, Turkey.

Department of Pediatric Surgery, Recep Tayyip Erdogan University of Medical Faculty, Rize, Turkey.

出版信息

J Lab Physicians. 2014 Jul;6(2):117-20. doi: 10.4103/0974-2727.141511.

DOI:10.4103/0974-2727.141511
PMID:25328338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4196359/
Abstract

Littoral cell angioma (LCA) is a rare, benign primary vascular neoplasm of the spleen. The tumor originates from the littoral cells lining the sinuses of the red pulp of the spleen. Preoperative distinction of this tumor from other benign or malign splenic lesions is difficult. Radiologically most cases present as multiple nodules. Definitive diagnosis can only be made histopathologically and immunohistochemically following splenectomy. This clinical situation can coexist with various malignancies and autoimmune disorders. Even though, it is mostly benign, since it has the potential to become malignant after splenectomy, long-term follow-up is required. We present an LCA case, which appeared as a solitary mass in the spleen of an 11-year-old girl with abdominal pain admitted to our hospital.

摘要

脾窦岸细胞血管瘤(LCA)是一种罕见的脾脏原发性良性血管肿瘤。该肿瘤起源于脾红髓血窦内衬的岸细胞。术前将此肿瘤与其他良性或恶性脾脏病变区分开来很困难。在放射学上,大多数病例表现为多发结节。只有在脾切除术后通过组织病理学和免疫组织化学检查才能做出明确诊断。这种临床情况可与各种恶性肿瘤和自身免疫性疾病共存。尽管它大多是良性的,但由于脾切除术后有恶变的可能,因此需要长期随访。我们报告一例LCA病例,该病例表现为一名因腹痛入院的11岁女孩脾脏中的孤立肿块。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fbf/4196359/88dc3be3decb/JLP-6-117-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fbf/4196359/71567963bab2/JLP-6-117-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fbf/4196359/d907cb62e6c1/JLP-6-117-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fbf/4196359/5078fe92fab3/JLP-6-117-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fbf/4196359/c7d5902b8b7d/JLP-6-117-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fbf/4196359/88dc3be3decb/JLP-6-117-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fbf/4196359/71567963bab2/JLP-6-117-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fbf/4196359/d907cb62e6c1/JLP-6-117-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fbf/4196359/5078fe92fab3/JLP-6-117-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fbf/4196359/c7d5902b8b7d/JLP-6-117-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fbf/4196359/88dc3be3decb/JLP-6-117-g005.jpg

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本文引用的文献

1
Littoral cell angioma of the spleen--a surprising cause of anemia.脾脏的边缘区细胞血管瘤——贫血的一个惊人病因。
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Littoral-cell angioma of the spleen.脾脏边缘区血管细胞瘤。
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Is littoral cell angioma of the spleen as rare as previously believed in the pediatric population?脾脏的沿岸细胞血管瘤在儿科人群中是否如之前认为的那样罕见?
Folia Histochem Cytobiol. 2012 Oct 8;50(3):480-5. doi: 10.5603/19761.
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Littoral cell angioma of the spleen.脾脏的沿岸细胞血管瘤。
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Splenic vascular tumors: a histologic, immunophenotypic, and virologic study.脾脏血管肿瘤:一项组织学、免疫表型及病毒学研究
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